Results 61 to 70 of about 4,686,984 (308)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Prediction of quality software quality indicators with applied modifications of integrated gradiates methods

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
The article is devoted to modern software systems (SS) and improving their quality using machine learning methods, including the Integrated Gradients (IG) method.
Anton Shantyr   +4 more
doaj   +1 more source

Information technologies, embodiment and growth [PDF]

open access: yes
This paper studies the conditions under which an IT revolution may endogenously occur. To this end, we construct an endogenous growth multisectoral model with a preeminent IT sector.
Boucekkine, Raouf, de la Croix, David
core  

Locating the information: applications, technologies and future aspects [PDF]

open access: yes, 2010
In today’s world, the demand for information is growing rapidly with respect to the human curiosity to explore the inside and the outside of our planet.
Bentum, Mark   +2 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

STATISTICAL PROPERTIES OF THE PSEUDORANDOM SEQUENCE GENERATION ALGORITHM

open access: yesScientific Journal of Astana IT University
One of the most important issues in the design of cryptographic algorithms is studying their cryptographic strength. Among the factors determining the reliability of cryptographic algorithms, a good pseudorandom sequence generator, which is used for key ...
Ardabek Khompysh   +4 more
doaj   +1 more source

Organizational Redesign, Information Technologies and Workplace Productivity [PDF]

open access: yes
Using a large longitudinal, nationally representative workplace-level dataset, we explore the productivity gains associated with computer use and organizational redesign.
Benoit Dostie, Rajshri Jayaraman
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Quality - Information Technologies - Consumer

open access: yesAmfiteatru Economic, 2011
Companies and consumers live in a world where the Internet is one of its defining elements, information technologies increasingly marking all the activities undertaken by them. With increased access to information, with a strong desire for knowledge, and
Vasile Dinu
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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