Results 61 to 70 of about 1,320,225 (265)

CONCEPT OF AUTOMATED RESPONSE TO THREATS IN CORPORATE DATABASES IN REAL-TIME MODE

Кібербезпека: освіта, наука, техніка
The article presents a concept of automated real-time threat response in corporate databases, developed with consideration of current trends in cyber threat evolution and the limitations of existing protection mechanisms. The relevance of the research is
Світлана Легомінова, Тетяна Капелюшна, Юрій Щавінський, Михайло Запорожченко, Олександр Будзинський   +4 more
doaj   +1 more source

First results in the development of a mobile robot with trajectory planning and object recognition capabilities

Open Engineering, 2016
The use of mobile robots is becoming popular in many areas of service because they ensure safety and good performance while working in dangerous or unreachable locations. Areas of application of mobile robots differ from educational research to detection
Islamgozhayev Talgat, Kalimoldayev Maksat, Eleusinov Arman, Mazhitov Shokan, Mamyrbayev Orken   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Prediction of quality software quality indicators with applied modifications of integrated gradiates methods

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
The article is devoted to modern software systems (SS) and improving their quality using machine learning methods, including the Integrated Gradients (IG) method.
Anton Shantyr, Olha Zinchenko, Kamila Storchak, Andrii Bondarchuk, Yuriy Pepa   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

STATISTICAL PROPERTIES OF THE PSEUDORANDOM SEQUENCE GENERATION ALGORITHM

Scientific Journal of Astana IT University
One of the most important issues in the design of cryptographic algorithms is studying their cryptographic strength. Among the factors determining the reliability of cryptographic algorithms, a good pseudorandom sequence generator, which is used for key ...
Ardabek Khompysh, Kunbolat Algazy, Nursulu Kapalova, Kairat Sakan, Dilmukhanbet Dyusenbayev   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Numerical simulation of two-phase filtration in the near well bore zone

Open Engineering, 2018
On the basis of the fundamental laws of energy conservation, nonstationary processes of filtration of two-phase liquids in multilayered reservoirs in the near well bore zone are considered.
Maksat Kalimoldayev, Kalipa Kuspanova, Kulyash Baisalbayeva, Orken Mamyrbayev, Assel Abdildayeva   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source