Results 41 to 50 of about 21,736,361 (314)

Self-Corrective Sensor Fusion for Drone Positioning in Indoor Facilities

open access: yesIEEE Access, 2021
Drones may be more advantageous than fixed cameras for quality control applications in industrial facilities, since they can be redeployed dynamically and adjusted to production planning.
Francisco Javier Gonzalez-Castano   +5 more
doaj   +1 more source

Information technology in education

open access: yesProcedia Computer Science, 2011
AbstractWith increasing knowledge and technological progress of society; our country requires learning skills that could help it keep pace with the development of science and technology. Educational systems in a community and consequently education will not be able to separate from other social institutions, national and international interactions ...
Farideh Hamidi   +3 more
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The concept of reducing the man-made impact of launches of the promising Irtysh launch vehicle in the impact areas of the Baikonur cosmodrome [PDF]

open access: yesОмский научный вестник: Серия "Авиационно-ракетное и энергетическое машиностроение", 2019
Scientific and methodological approaches to minimizing the man-made impact of launches of promising carrier rockets of the «Irtysh» type by oxygen-kerosene main liquid-propellant rocket engines of the Baiterek rocket complex in areas of falling of the ...
B. T. Suimenbayev   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Minutes: Senate Committee on Information Technologies: February 10, 2020

open access: yes, 2020
University of Minnesota: Senate Committee on Information Technologies. (2020). Minutes: Senate Committee on Information Technologies: February 10, 2020.
University of Minnesota: Senate Committee on Information Technologies
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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