Results 101 to 110 of about 8,796,152 (351)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Technology Advancement Influence in Accounting and Information System Fields [PDF]

open access: yes, 2018
This research serves to relate the accounting and information technology fields. The information in the research documents changes in the accounting and information technology fields, and how the fields are expected to change in the coming years.
Gordon, Shannon
core   +2 more sources

Technological Infrastructure in Information Technology Industries

open access: yes, 1996
Both traditional and modern uses of the term infrastructure are related to “synergies”, what economists call positive externalities, that are incompletely appropriated by the suppliers of goods and services within an economic system. The traditional idea of infrastructure was derived from the observation that the private gains from the construction and
openaire   +4 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Information technology and efficiency in trucking [PDF]

open access: yes
In this paper, we develop an econometric model to estimate the impacts of Electronic Vehicle Management Systems (EVMS) on the load factor (LF) of heavy trucks using data at the operational level.
Denis Bolduc   +3 more
core   +3 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Information Technology for Preserving the Bulgarian Folklore Heritage [PDF]

open access: yes, 2013
Folk songs are an important and essential part of the Bulgarian cultural heritage. Following the traditions of the 20th century in publishing Bulgarian folk songs, we prepared the book “Folk Songs from Thrace” [3] with scores and lyrics recorded from ...
Kirov, Nikolay, Peycheva, Lozanka
core  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Tracking down on 50-year History of Research about Information Management and Technology in Korea

open access: yesJournal of Information Science Theory and Practice, 2013
Dept. of Domestic Information Information Service Center Korea Institute of Science and Technology Information
doaj   +1 more source

The Federal Role in Promoting Health Information Technology [PDF]

open access: yes, 2009
Outlines the need to expand adoption of health information technology to improve healthcare quality and efficiency; the financial, technical, and logistical challenges; and providers' concerns.
David Blumenthal
core  

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