Results 111 to 120 of about 3,709,120 (314)

Computing & Information Services, Vol. XVI, No. 4 [PDF]

open access: yes, 1987
Newsletter distributed by the SMU Computer Center for July 1987. Issue includes information about the computer center itself along with highlighted pieces about technology of the ...
Southern Methodist University. Office of Information Technology
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Computing & Information Services, Vol. XVI, No. 3 [PDF]

open access: yes, 1987
Newsletter distributed by the SMU Computer Center for June 1987. Issue includes information about the computer center itself along with highlighted pieces about technology of the ...
Southern Methodist University. Office of Information Technology
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Privacy for Electronic Information [PDF]

open access: yes, 2011
Information ...
Office of the Vice President for Information Technology
core  

What's New About the New Economy? IT, Economic Growth and Productivity [PDF]

open access: yesInternational Productivity Monitor, 2001
The U.S. economy performed extraordinarily well in the 1990s. Unemployment has dropped to historically low rates; the federal government is awash with revenues, and after a quarter century of near stagnation, productivity growth is soaring.
Barry P. Bosworth, Jack E. Triplett
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Computing and Information Services Newsletter, Vol. XIX, No. 2 [PDF]

open access: yes, 1988
Newsletter distributed by the SMU Computer Center for March 1988. Issue includes information about the computer center itself along with highlighted pieces about technology of the ...
Southern Methodist University. Office of Information Technology
core  

Futur-forecast of developing library technology within forming a new information-technological paradigm

open access: yesБиблиосфера, 2014
The perspectives of information technologies development and their growing influence on society, as well as new requirements for developing strategies of libraries in the medium and longer term are considered.
N. S. Redkina
doaj  

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