Results 101 to 110 of about 3,709,120 (314)

Ethics and Information Technology

open access: yesAustralasian Journal of Information Systems, 1997
The versatility and adaptability of information technology (IT) offer many potential benefits to society, its organisations and its citizens, but there are also associated risks. The social and ethical implications of this technology warrant special attention and have resulted in the creation of information ethics as a discrete area of study.
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Information Technology Investment Planning [PDF]

open access: yes, 2016
"Revision history ... 10/13/2016: Revised planning requirements to reflect process updates. In addition, transferred policy content to a new State of Ohio Administrative Policy Template. Re???numbered policy to IT???02 to be consistent with new numbering
Ohio. Office of Information Technology.
core  

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

OIT Technology News: August 2012 [PDF]

open access: yes, 2012
Online newsletter distributed by the SMU Office of Information Technology available for students, faculty, and staff at SMU. This newsletter covers topics related to technology, and includes information regarding the Office of Information Technology and ...
Southern Methodist University. Office of Information Technology
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Information technology benchmark/utilization report [PDF]

open access: yes, 2005
Biennial; Fiscal years 2000/2001-; Title from PDF t.p. (viewed Sept. 10, 2002); Vol.
Ohio. Office of Information Technology. Investment and Governance Division
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Computing & Information Services, Vol. XVI, No. 5 [PDF]

open access: yes, 1987
Newsletter distributed by the SMU Computer Center for August 1987. Issue includes information about the computer center itself along with highlighted pieces about technology of the ...
Southern Methodist University. Office of Information Technology
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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