Results 31 to 40 of about 2,781,627 (318)
FEBS Letters, EarlyView.In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri +8 more
wiley +1 more source
Tūzī yǔ dàng’àn xuékān, 2023 "In response to the arrival of the age of information technology, the Curriculum Guidelines of 12-year Basic Education published by the Taiwanese government in 2019 incorporates information technology a standalone academic subject.
Wen-Hui Lin, Shih-Chuan Chen
doaj +1 more source
Knowledge for a warmer world: a patent analysis of climate change adaptation technologies [PDF]
arXiv, 2021 Technologies can help strengthen the resilience of our economy against existential climate-risks. We investigate climate change adaptation technologies (CCATs) in US patents to understand (1) historical patterns and drivers of innovation; (2) scientific and technological requirements to develop and use CCATs; and (3) CCATs' potential technological ...
arxiv
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Exploring assessment method of technological advancement based on literature cross-citation [PDF]
arXiv, 2023 Assessing advancements of technology is essential for creating science and technology policies and making informed investments in the technology market. However, current methods primarily focus on the characteristics of the technologies themselves, making it difficult to accurately assess technologies across various fields and generations.
arxiv
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
CLASSIFICATION OF INFORMATION TECHNOLOGY
Открытое образование (Москва), 2016 We offer a multi-level classification of IT based on bottom to up strata distribution of techniques, tools and hardware intended to work with information depending on their degree of complexity – from the tools of human-computer communication, collection,
Violetta N. Volkova +3 more
doaj +1 more source
HEALTH INFORMATION TECHNOLOGY IN EXCHANGE OF HEALTH INFORMATION [PDF]
Journal of IMAB, 2016 Health information technology involves the exchange of health information in an electronic environment. Data protection is comprised of many elements, including where the data resides, how it is used, and who has access to it.
Jordan Deliversky
doaj +1 more source
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
Information technology and information system in reengineering [PDF]
Acta Montanistica Slovaca, 2007 Author describes using information technology and information technology (IS/IT) in the reengineering process in this paper. Only companies able to react to the real-world impulses of the volatile environment in the global market and where management ...
Petr Wolf
doaj