Results 41 to 50 of about 9,323,869 (343)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

2012 Grantmakers Information Technology Survey Report [PDF]

open access: yes, 2012
Together the Technology Affinity Group (TAG) and Grants Managers Network (GMN) conducted an information technology survey of grantmaking organizations in July 2012.
Lisa Pool
core  

INCF Lithuanian Workshop on Neuroscience and Information Technology [PDF]

open access: yes, 2012
The aim of this workshop was to give a current overview of neuroscience and informatics research in Lithuania, and to discuss the strategies for forming the Lithuanian Neuroinformatics Node and becoming a member of INCF. The workshop was organized by Dr.
Auš
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Information Technology Governance Using Control Objectives for Information and Related Technology: Review

open access: yesJuTISI (Jurnal Teknik Informatika dan Sistem Informasi)
Information technology governance (ITG) is organizational management that aims to ensure the implementation of IT is carried out effectively and efficiently in realizing organizational goals.
Yoppy Mirza Maulana
doaj   +1 more source

The Information Technology Project

open access: yesMATEC Web of Conferences, 2016
The author raises the question of suitable use of different software in construction. Currently, there are several design techniques using computer technology. The various stages of the project require their parameters and software settings.
Smirnov Andrei
doaj   +1 more source

Information Technology & psychiatry

open access: yesArchives of Mental Health, 2010
The advances in the area of Information Technology has a pervasive influence on the society. There is no field where IT cannot help in improving its quality. IT has improved the processing speed of information, ease with which information can be transferred and shared.
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Information technology in pharmacovigilance: Benefits, challenges, and future directions from industry perspectives

open access: yesDrug, Healthcare and Patient Safety, 2009
Zhengwu LuClinical Research Department, Abbott Vascular, Santa Clara, CA, USAAbstract: Risk assessment during clinical product development needs to be conducted in a thorough and rigorous manner.
Zhengwu Lu
doaj  

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