Results 61 to 70 of about 9,288,361 (297)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Information Technology & psychiatry
Archives of Mental Health, 2010 The advances in the area of Information Technology has a pervasive influence on the society. There is no field where IT cannot help in improving its quality.
K Ashok Reddy
doaj
The Information Technology Project
MATEC Web of Conferences, 2016 The author raises the question of suitable use of different software in construction. Currently, there are several design techniques using computer technology. The various stages of the project require their parameters and software settings.
Smirnov Andrei
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Drug, Healthcare and Patient Safety, 2009 Zhengwu LuClinical Research Department, Abbott Vascular, Santa Clara, CA, USAAbstract: Risk assessment during clinical product development needs to be conducted in a thorough and rigorous manner.
Zhengwu Lu
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Cognition and Technology in Education: Knowledge and Information - Language and Discourse
Miscelánea: A Journal of English and American Studies, 2002 Almost from the beginnings of education, technologies in a broad sense have been present, each with its own merits and drawbacks. Computer technology has been hailed with great promise, but early results have been disappointing insofar as computer ...
Robert de Beaugrande
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Selected topics in information technology : series 1 [PDF]
, 2017 This volume is devoted to the recent developments on Information and Communication Technology (ICT) systems and applications spread across various domain. It seeks to illustrate the potential of Information Technology for a wide range of applications via
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source