Results 61 to 70 of about 8,942,452 (348)

Information Technology & psychiatry

Archives of Mental Health, 2010
The advances in the area of Information Technology has a pervasive influence on the society. There is no field where IT cannot help in improving its quality.
K Ashok Reddy
doaj  

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

The role of Information Technology in Education [PDF]

, 2017
Education and study are vital processes in everyday life. From the first birthday to the last day a person learns every day. We are taught by our parents, people around us, nature, and circumstances.
Mishkov, V. I., Stativa, Bogdan, Zabolotnikova, V. V.   +2 more
core  

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Technology infrastructure in information technology industries [PDF]

not availableeconomics of technology business administration and ...
Steinmueller,W. Edward
core   +1 more source

Information Technology(IT): A New Revolution In Urban Health Development [PDF]

پیاورد سلامت, 2012
Background and Aim: Urban health is one of the challenges of the 21st century. Rapid growth and expanding urbanization have implications for health. In this regard, information technology can remove a large number of modern cities' problems.
Marjan Ghazi Saeedi, Reza Safdari, Maryam Zahmatkeshan   +2 more
doaj   +2 more sources

Tourism Information Technology [PDF]

Journal of Tourism Futures, 2020
Maya Ivanova, Stanislav Ivanov
doaj   +1 more source

Reflections on the implications of technology-mediated learning: A teacher educator perspective

Journal of Teaching and Learning, 2009
In this paper, I report on how my practice was influenced by re-designing an existing introductory teacher education course that included an online component.
Sal J Badali
doaj   +1 more source