Results 71 to 80 of about 9,323,869 (343)

Tourism Information Technology [PDF]

open access: yesJournal of Tourism Futures, 2020
Maya Ivanova, Stanislav Ivanov
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Developments in information technology, networks and services [PDF]

open access: yes, 2002
A review of policy issues facing Scotland as it faces changing from an industrial society to a knowledge led economy. Identifies the key developments, external trends and internal pressures which library policy makers face.
Law, Derek
core  

Reflections on the implications of technology-mediated learning: A teacher educator perspective

open access: yesJournal of Teaching and Learning, 2009
In this paper, I report on how my practice was influenced by re-designing an existing introductory teacher education course that included an online component.
Sal J Badali
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Valuation of Information Technology Investment Using the Discounted Cash Flow and Real Options Analysis [PDF]

open access: yes, 2012
PT. Telekomunikasi Indonesia (Telkom) planned to develop an IT-based integrated Customer Relationship Management (CRM) system called Unified TICARES in 2012 as a part of corporate strategic initiatives.
Anggono, A. H. (Achmad)   +1 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Graphical Technology Information Dissemination [PDF]

open access: yes, 2014
Graphical technologies cover a wide range of topics from the modeling software used by animators, to algorithms used in scientific simulations of natural phenomena, to the growing 3D printing industry. While graphical technologies are still relatively
Andrews, Aaron
core  

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