Results 111 to 120 of about 1,839,744 (376)

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

open access: yesAdvanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra   +23 more
wiley   +1 more source

The influence of internal factors, national culture and artificial intelligence on audit technology usage with IT governance as a mediator

open access: yesJurnal Akuntansi dan Auditing Indonesia
This study aims to examine the intention and actual usage of audit technology in Indonesian Public Accounting Firms by analyzing the effects of internal factors, national culture, and Artificial Intelligence (AI), with Information Technology (IT ...
Recky Syahnal El Natsir   +1 more
doaj   +1 more source

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

open access: yesAdvanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang   +8 more
wiley   +1 more source

Machine learning and human‐machine trust in healthcare: A systematic survey

open access: yesCAAI Transactions on Intelligence Technology
As human‐machine interaction (HMI) in healthcare continues to evolve, the issue of trust in HMI in healthcare has been raised and explored. It is critical for the development and safety of healthcare that humans have proper trust in medical machines ...
Han Lin   +6 more
doaj   +1 more source

Reputation Concerns and Herd Behavior of Audit Committees - A Corporate Governance Problem [PDF]

open access: yes
This paper offers an explanation for audit committee failures within a corporate governance context. We consider a setting in which the management of a firm sets up financial statements that are possibly biased.
Barbara Schöndube-Pirchegger   +1 more
core  

THE UTILIZATION OF INFORMATION AND COMMUNICATION TECHNOLOGY TO SUPPORT LEARNING-BASED PROCESS OF PDCA QUALITY ISO 9001: 2008 IWA2 [PDF]

open access: yes, 2013
Education Institution is the service provider institution, therefore the customers who get involved demanding the guarantee fulfill their needs suit to the promise have given by the company consistently and continuously.
Barnad, Barnad
core  

Machine Learning for Green Solvents: Assessment, Selection and Substitution

open access: yesAdvanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta   +4 more
wiley   +1 more source

Continuous Auditing (Audit Masa Mendatang yang Membangun Kemampuan Pengauditan terotomatisasi)

open access: yesJurnal Akuntansi, 2014
Technological advances (e.g. e-commerce and the internet) have changed business practices and the process of recording and storing business transactions.
Riki Martusa
doaj   +1 more source

Corporate Governance, Reputation Concerns, and Herd Behavior [PDF]

open access: yes
This paper offers an explanation for audit committee failures within a corporate governance context. We consider a setting in which the management of a firm sets up financial statements that are possibly biased.
Barbara Schöndube-Pirchegger
core  

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