Results 141 to 150 of about 21,934,227 (308)

On the interplay between Shannon's information measures and reliability criteria

open access: yes, 2009
In the literature, different reliability criteria are used in different coding theorems. Weak secrecy and strong secrecy are frequently used in information-theoretic security problems and their implications in terms of the average symbol error ...
Siu-Wai Ho, Ho, S.W.
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Integrated Information Theory and Isomorphic Feed-Forward Philosophical Zombies

open access: yes, 2019
Any theory amenable to scientific inquiry must have testable consequences. This minimal criterion is uniquely challenging for the study of consciousness, as we do not know if it is possible to confirm via observation from the outside whether or not a ...
Sara I. Walker, Jake R. Hanson
core   +1 more source

Fog Computing Meets URLLC: Energy Minimization of Task Partial Offloading for URLLC Services

open access: yesIEEE Access
Ultra-high reliability and ultra-low latency communication (URLLC) are critical challenges for upcoming 6G applications. Cloud computing and mobile edge computing (MEC) offer potential solutions but incur high deployment and maintenance costs due to ...
Chenhao Shi   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

A Theory of Inaccessible Information

open access: yesQuantum
What would be the consequences if there were fundamental limits to our ability to experimentally explore the world? In this work we seriously consider this question. We assume the existence of statements whose truth value is not experimentally accessible.
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Compact H-Plane CLAF-SIW Horn Antenna With Phase Front Correction

open access: yesIEEE Access
This work presents an H-plane contactless air-filled substrate-integrated waveguide (CLAF-SIW) horn antenna, whose directivity is enhanced by incorporating a metalens along the horn flaring.
Andres Biedma-Perez   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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