Results 131 to 140 of about 21,934,227 (308)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Frontiers in Network PhysiologyUnderstanding the underlying dynamics of complex real-world systems, such as neurophysiological and climate systems, requires quantifying the functional interactions between the system units under different scenarios.
Laura Sparacino +7 more
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Structural and Symbolic Information in the Context of the General Theory of Information
, 2017 The general theory of information, which includes syntactic, semantic, pragmatic, and many other special theories of information, provides theoretical and practical tools for discerning a very large diversity of different kinds, types, and classes of ...
Mark Burgin, Rainer Feistel
core +1 more source
IEEE AccessIn the medical domain, particularly in intensive care units (ICUs), the immense volume of patient data presents a significant challenge for clinicians, often resulting in the oversight of critical information or excessive time consumption in accessing it.
Ahmad Ayad +3 more
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Early thrombus detection in ECMO with optimized impedance measurements: A simulative study
Journal of Electrical BioimpedanceExtracorporeal oxygenation supports patients with severe cardiac or respiratory failure, with the oxygenator providing critical gas exchange. Thrombus formation in the oxygenator can impair efficiency and increase risks such as hemolysis and embolism ...
Slapal Filip +3 more
doaj +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Information quality management: theory and applications
, 2007 [Publisher's Description]: The Internet and mobile commerce bring with them ubiquitous connectivity, real-time access, and overwhelming volumes of data and information.
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