Results 111 to 120 of about 21,934,227 (308)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Conscious Causality, Observer-Observed Simultaneity, and the Problem of Time for Integrated Information Theory. [PDF]

open access: yesEntropy (Basel)
Without proven causal power, consciousness cannot be integrated with physics except as an epiphenomenon, hence the term ‘hard problem’. Integrated Information Theory (IIT) side-steps the issue by stating that subjective experience must be ...
Sanfey J.
europepmc   +2 more sources

Vertex Graph-Coloring-Based Pilot Assignment With Location-Based Channel Estimation for Massive MIMO Systems

open access: yesIEEE Access, 2018
Massive multiple-input multiple-output (MIMO) is considered as a promising technique in wireless communication systems, which contains cellular base stations equipped with a very large number of antennas to serve multiple users.
Hieu Trong Dao, Sunghwan Kim
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Extended economic models for information systems balance theory

open access: yes, 2014
Even though we are in the information age, we do not have quantitative, objective tools to evaluate organisational information systems. This paper contributes a fundamental theory: information systems balance theory for this purpose.
Jianming Yong   +3 more
core   +1 more source

Low-Complexity Gaussian Detection for MIMO Systems

open access: yesJournal of Electrical and Computer Engineering, 2010
For single-carrier transmission over delay-spread multi-input multi-output (MIMO) channels, the computational complexity of the receiver is often considered as a bottleneck with respect to (w.r.t.) practical implementations.
Tianbin Wo, Peter Adam Hoeher
doaj   +1 more source

Disjoint Pilot Power and Data Power Allocation in Multi-Cell Multi-User Massive MIMO Systems

open access: yesIEEE Access, 2018
In this paper, we consider pilot and data power allocation in multi-cell multi-user massive multiple-input multiple-output (MIMO) systems to maximize the summation of spectral efficiency (sum SE).
Hieu Trong Dao, Sunghwan Kim
doaj   +1 more source

Information theory in the brain [PDF]

open access: yesCurrent Biology, 2000
Shannon CE: A mathematical theory of communication.Bell System Tech J 1948, 27:379-423;623-656. (Reprinted in Claude Elwood Shannon: Collected Papers. Edited by Sloane NJA and Wyner AD. New York: IEEE Press; 1993. Also available at http://cm.bell-labs.com/cm/ms/what/shannonday/paper.html)Rieke FM, Warland DK, de Ruyter van Steveninck R, Bialek W ...
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Scaling behaviour and critical phase transitions in integrated information theory [PDF]

open access: yes, 2019
Integrated Information Theory proposes a measure of conscious activity (Phi), characterised as the irreducibility of a dynamical system to the sum of its components. Due to its computational cost, current versions of the theory (IIT 3.0) are difficult to
Miguel Aguilera, Aguilera, Miguel
core   +1 more source

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