Results 161 to 170 of about 21,680,450 (363)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Compact H-Plane CLAF-SIW Horn Antenna With Phase Front Correction

open access: yesIEEE Access
This work presents an H-plane contactless air-filled substrate-integrated waveguide (CLAF-SIW) horn antenna, whose directivity is enhanced by incorporating a metalens along the horn flaring.
Andres Biedma-Perez   +3 more
doaj   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Early thrombus detection in ECMO with optimized impedance measurements: A simulative study

open access: yesJournal of Electrical Bioimpedance
Extracorporeal oxygenation supports patients with severe cardiac or respiratory failure, with the oxygenator providing critical gas exchange. Thrombus formation in the oxygenator can impair efficiency and increase risks such as hemolysis and embolism ...
Slapal Filip   +3 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

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