Results 81 to 90 of about 750,104 (309)

Entropy Region and Network Information Theory [PDF]

open access: yes, 2011
This dissertation takes a step toward a general framework for solving network information theory problems by studying the capacity region of networks through the entropy region.
Sormeh Shadbakht, Shadbakht, Sormeh
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Still Minding the Gap? Reflecting on Transitions between Concepts of Information in Varied Domains

open access: yesInformation, 2020
This conceptual paper, a contribution to the tenth anniversary Special Issue of Information, gives a cross-disciplinary review of general and unified theories of information.
David Bawden, Lyn Robinson
doaj   +1 more source

Entropy and information causality in general probabilistic theories

open access: yesNew Journal of Physics, 2010
We investigate the concept of entropy in probabilistic theories more general than quantum mechanics, with particular reference to the notion of information causality recently proposed by Pawlowski et. al. (arXiv:0905.2992). We consider two entropic quantities, which we term measurement and mixing entropy. In classical and quantum theory, they are equal,
Barnum, Howard   +7 more
openaire   +6 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Orders between channels and implications for partial information decomposition

open access: yes, 2023
The partial information decomposition (PID) framework is concerned with decomposing the information that a set of random variables has with respect to a target variable into three types of components: redundant, synergistic, and unique.
Gomes, André F. C.   +3 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Modified Landauer Principle According to Tsallis Entropy

open access: yesEntropy
The Landauer principle establishes a lower bound in the amount of energy that should be dissipated in the erasure of one bit of information. The specific value of this dissipated energy is tightly related to the definition of entropy. In this article, we
Luis Herrera
doaj   +1 more source

Paradigms of Cognition

open access: yesEntropy, 2017
An abstract, quantitative theory which connects elements of information —key ingredients in the cognitive proces—is developed. Seemingly unrelated results are thereby unified.
Flemming Topsøe
doaj   +1 more source

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