Results 51 to 60 of about 2,285,691 (245)

Neutrinos and Future Concordance Cosmologies

open access: yes, 2008
We review the free parameters in the concordance cosmology, and those which might be added to this set as the quality of astrophysical data improves. Most concordance parameters encode information about otherwise unexplored aspects of high energy physics,
Adshead P   +10 more
core   +1 more source

Application of Trend Impact Analysis for predicting future fruit consumption [PDF]

open access: yes, 2009
Knowledge of those aspects that motivate consumers towards more fruit consumption is necessary in order to implement policies to stimulate fruit consumption.
Benninga, J., Hennen, W.H.G.J.
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Using the Wild Bootstrap to Quantify Uncertainty in Mean Apparent Propagator MRI

open access: yesFrontiers in Neuroinformatics, 2019
Purpose: Estimation of uncertainty of MAP-MRI metrics is an important topic, for several reasons. Bootstrap derived uncertainty, such as the standard deviation, provides valuable information, and can be incorporated in MAP-MRI studies to provide more ...
Xuan Gu   +8 more
doaj   +1 more source

Pengaruh Sistem Desentralisasi Dan Ketidakpastian Lingkungan Terhadap Kinerja Manajerial Yang Dimoderasi Oleh Asimetri Informasi

open access: yesJurnal Akuntansi, 2020
The purpose of this study was to examine and analyze the influence of decentralization systems and environmental uncertainty on managerial performance. This study also examine and analyze the role of information asymmetry as a moderating variable in the ...
Merna Merna
doaj   +1 more source

Robust visual odometry using uncertainty models [PDF]

open access: yes, 2011
In dense, urban environments, GPS by itself cannot be relied on to provide accurate positioning information. Signal reception issues (e.g. occlusion, multi-path effects) often prevent the GPS receiver from getting a positional lock, causing holes in the ...
B. Kitt   +3 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Firms' investment decisions in response to demand and price uncertainty [PDF]

open access: yes
We estimate the effect of demand and price uncertainty on firms’ investment decisions from a panel of manufacturing firms. Uncertainty measures are derived from firms’ subjective qualitative expectations. They are close to their theoretical counterparts,
Fuss, Catherine, Vermeulen, Philip
core   +3 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

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