Results 141 to 150 of about 285,379 (265)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

The Impact of Healthcare Professionals' Characteristics on the Evaluation of Clinical Decision Support Systems: Insights from a Cross-Country Usability and Technology Acceptance Study of the iCARE Tool. [PDF]

J Med Syst
Nuutinen M, Hiltunen AM, Leskelä RL, Messo M, Salminen A, Lahelma M, de Almeida Mello J, Declercq A, Švihnosová O, Langmaierová K, Fialová D, Mammarella F, Liperoti R, Exmann C, van Hout H, Pešić V, Howard E, Stodolska A, Szczerbińska K, Alon M, Haavisto I.   +20 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Association between social media usefulness, depression, and self-esteem among adults with disabilities: a longitudinal panel study. [PDF]

Int J Equity Health
Kim DB, Lim JH, Ko J, Joo MJ, Park EC.
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Assessing the educational quality of YouTube videos on celiac plexus blocks: Expert review and AI-based evaluation. [PDF]

Interv Pain Med
Zhu J, Hao D, Yong RJ.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

How physicians embrace AI: insights from technology acceptance and trust theories. [PDF]

Front Digit Health
Cicin FN, Çetin Gürkan G.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Patient Perceptions of Artificial Intelligence in Diabetes Self-Management: Cross-Sectional Survey Study. [PDF]

JMIR Form Res
Martini N, Dhaliwal NK, Alipour E, Scahill S, Sajtos L.   +4 more
europepmc   +1 more source