Buildingthe User-Oriented Information Service Systemof Smart City
With the deve1opment of information techno1ogy and the growth of the smart city, the pub1ic demand for information techno1ogy more persona1ized and diversified, and higher requirements for the information services of the smart city are put forward.The ...
Shuguang Lin +3 more
doaj
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Selecting the Best End-User Device from User Perspective for Hospital Information Systems (HIS)
Introduction: Choosing the right type of device is important to support users of Health Information Systems. In addition to cost, durability and simplicity, staffing levels and hospital workflows affect in the selected.
Mahboubeh Eslami +2 more
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Usability evaluation of a Halal Food Tracer information system using ISO 25023 and UWIS models. [PDF]
Susanty A +3 more
europepmc +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Real-Time Detection and Prediction-Aided Dynamic Location Area Design for High-Mobility Users Based on LEO Satellites. [PDF]
Chang A, Ding X, Zhang G.
europepmc +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Assessing the use of the input of care users in long-term care homes during 2020-2023 in the Netherlands: an exploratory study. [PDF]
Palimetaki F, Schouteten R.
europepmc +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source

