Results 141 to 150 of about 636,467 (265)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

User-Centered Diabetes Self-Management App (DiabAid Nexus) in Sub-Saharan Africa: Development and Usability Study. [PDF]

J Med Internet Res
Aboye GT, Gebremichael EH, Simegn GL, Aerts JM.   +3 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

MyLungHealth, a Patient-Facing Education Tool for Lung Cancer Screening: Qualitative User-Centered Design Study. [PDF]

JMIR Form Res
Balbin CA, Stevens L, Dalrymple R, Tiase VL, Kaphingst KA, Stevens ER, Kukhareva PV, Caverly TJ, Del Fiol G, Mann D, Kwon J, Fagerlin A, Butler JM, Kawamoto K.   +13 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Modeling Behavioral Determinants of Following and Verifying AI-Generated Health Advice: The Roles of eHealth Literacy, Cognitive Load, and Technology Self-Efficacy. [PDF]

J Multidiscip Healthc
Alhur AA, Alnasser B.
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Chinese Mobile Health Apps for Preventing and Managing Pelvic Floor Dysfunction: Quality Assessment and Content Analysis. [PDF]

J Med Internet Res
Song Y, Deng X, Hu T, Feng S, Xing L.
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Protocol for detecting genome-wide introgressed genes and evaluating their functional legacy. [PDF]

STAR Protoc
Jiao Z, Ren Z, Hu C, Ma X, Zhang GQ, Chen LJ, Wei G, Peng DH, Luo YB, Lan S, Liu ZJ.   +10 more
europepmc   +1 more source