Results 181 to 190 of about 25,109,469 (289)

The information value of early career productivity in mathematics: a ROC analysis of prediction errors in bibliometricly informed decision making. [PDF]

Scientometrics, 2016
Lindahl J, Danell R.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Bayesian Value-of-Information Analysis: An Application to a Policy Model of Alzheimer's Disease [PDF]

A framework is presented which distinguishes the conceptually separate decisions of which treatment strategy is optimal from the question of whether more information is required to inform this choice in the future.
S. S. Araki, M. C. Weinstein, P. J. Neumannn, K. Claxton   +3 more
core  

Perception of Information Value in the Composition of Complex Text

Langues & Cultures
This study explores perception of information value as a communication strategy in complex text composition, using television advertisements of food consumer goods as an example.
Jackton MIDIGO, Damaris NYAKOE
doaj  

Does C-reactive protein exhibit high prognostic information value in acute pulmonary embolism? A novel structural pathway for disease progression beyond classical statistical associations. [PDF]

PLoS One
Tukiendorf A, Feusette P.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Landslide susceptibility assessment in Tongguan District Anhui China using information value and certainty factor models. [PDF]

Sci Rep
Ding D, Wu Y, Wu T, Gong C.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The Social Value of Public Information with Costly Information Acquisition [PDF]

In a beauty contest framework, we show that more precise public information contributes to higher welfare when the precision of private information is endogenous.
Gianluca Femminis, Luca Colombo
core  

Landslide hazard assessment of an urban agglomeration in central Guizhou Province based on an information value method and SVM, bagging, DNN algorithm. [PDF]

Sci Rep
Luo J, Zhao Z, Li W, Huang L, Zhao W.
europepmc   +1 more source