Results 121 to 130 of about 14,095,467 (307)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Business Information Visualization

open access: yesCommunications of the Association for Information Systems, 1999
With the flood of data produced by today’s information systems, something must be done to allow business decision-makers to extract the information the data contains. The recent advances in visualization technologies provide the capability to begin to use human visual/spatial abilities to solve the abstract problems found in business.
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Dynamic Coordinated Email Visualization [PDF]

open access: yes, 2005
Many computer users receive hundreds (if not thousands) of emails per week; users often keep these emails and have many years of personal emails archived: users use their stored emails to manage appointments, to-do lists, and store useful information. In
Boukhelifa, Nadia   +3 more
core  

Adversarial Robustness of Deep Learning Models for Inland Water Body Segmentation From SAR Images

open access: yesIEEE Access
Segmentation of inland water bodies from Synthetic Aperture Radar (SAR) images is crucial for several applications, such as flood mapping and monitoring. While SAR sensors provide high-resolution, all-weather imagery, distinguishing water from water-like
Siddharth Kothari   +4 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Visualization-Panel for Provenance Data [PDF]

open access: yes, 2008
Today’s IT-systems are becoming more difficult. Their relationship together grows as well as their complexity. Currently a main requirement is for people to trust more in the results and have a better understanding of the functionality.
Kunde, Markus
core  

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