Results 71 to 80 of about 149,772 (265)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Church of war: propaganda and disinformation in Patriarch Kirill’s discourse on Russia’s aggression
Cogent Arts & HumanitiesThe Moscow Patriarchate holds a significant position within the Russian disinformation and propaganda system. Since the onset of the aggression against Ukraine in 2022, Patriarch Kirill (Vladimir Gundyayev) has fervently supported Russian military ...
Marcin Składanowski +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Вісник Харківського національного університету імені В.Н. Каразіна. Серія: Ìсторія України. Українознавство: історичні та філософські наукиThe purpose of the study. To investigate and analyze the problems of scientific thought and the evolution of the study of the volunteer movement in Ukraine. The research methodology.
Yevgenіі Teluha
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
RUDN Journal of Public Administration, 2016 At the present stage of the development of social relations the information acquires the value of the most important resource in global policy and world economy.
Dmitry V Yurkov
doaj
Value orientations of information culture as a key factor of society information security
Cхід, 2018 The article is devoted to an analysis of the essence of information culture as the main factor of security of a social information system in the context of globalization challenges of today’s information threats.
Irina Lomachinska
doaj +1 more source
The Information Environment of War
, 2008 This article observes high levels of anxiety about war in the present era, although wars are in decline. It addresses this paradox by distinguishing ideal-typical features of Industrial and Information War. Industrial War is fought predominantly between states over territory, harnesses industry and the military, and requires mass mobilisation of people
Gillan, Kevin +2 more
openaire +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source