Results 141 to 150 of about 3,049,300 (294)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Implementing electronic informed consent in rare disease genomics. [PDF]

Sci Rep
Ekholm K, Augustinsson A, Sundström J, Johansen C, Storgärds M, Ljöstad L, Taylan F, Ekblom E, Juran S, Ek M, Malmgren CI, Soller MJ, Friedman M, Thunström S, Lovmar L, Nordgren A, Ehrencrona H, Lindstrand A.   +17 more
europepmc   +1 more source

Informed consent: ethical issues and legislation in dentistry

, 2013
Arturo G. Rillo
openalex   +1 more source

Referee report. For: A pilot study to explore utility of electronic informed consent in a low- income setting; the case of a Controlled human infection study in Blantyre, Malawi [version 2; peer review: 4 approved with reservations]

Erisa Mwaka
openalex   +1 more source

Informed consent and communication of risk from radiological and nuclear medicine examinations: how to escape from a communication inferno

, 2004
Eugenio Picano
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Perceptions, practices, and barriers in surgical informed consent: A cross-sectional study from Sudan: Surgical Informed Consent in Sudan. [PDF]

Surg Pract Sci
Hassan IN, Ibrahim M, Yaqub S, Ibrahim M, Abdalla H, Aljaili G, Osman W, Abuassa N.   +7 more
europepmc   +1 more source

The Use of Informed Consent in Endodontic Treatment in Saudi Arabia: A Cross-Sectional Study [PDF]

Majed Almalki, Waad Khayat
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

When I say … informed consent. [PDF]

Med Educ
McGrath C, Palmgren PJ, Liljedahl M.
europepmc   +1 more source