Results 151 to 160 of about 461,960 (292)

[When the one who heals dies. The physician at the end of life]. [PDF]

Rev Med Inst Mex Seguro Soc
Anica-Malagón ED, Salgado-Abrego YN.
europepmc   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

History of whooping cough in Colombia: Endemic infant deaths, outbreaks and epidemics [PDF]

Biomedica
Idrovo ÁJ, Amaya-Castellanos C, Zapata-Bedoya S.   +2 more
europepmc   +1 more source

El concepto de biblioteca nacional a partir de los tres informes de la unesco sobre las bibliotecas nacionales: Sylvestre (1.987), Line (1.989) y Cornish (1.991)

, 2008
Between the years 1,987 and 1,991, UNESCO published three reports on national libraries. This article focuses on the concept of national library as presented in the cited authors.
Juan José Fuentes Romero
core  

Hyper‐Intense Tumor Peripheral Accumulation of Antibody‐Conjugated Iron Oxide Nanoparticles can Enable Breast Cancer Detection by Magnetic Particle Imaging

Advanced Science, EarlyView.
Tumor‐associated inflammation retains antibody‐targeted or non‐specific antibody conjugated nanoparticles within the tumor microenvironment. Magnetic Particle Imaging (MPI) enables non‐invasive detection and differentiation of tumors from other organs, owing to higher nanoparticle retention by inflammatory cells in the tumor periphery.
Preethi Korangath, Hayden Carlton, Theresa Wong, Sean Healy, Toby Sanders, Mason Song, Patrick W. Goodwill, Cordula Grüttner, Kathleen Gabrielson, Robert Ivkov   +9 more
wiley   +1 more source

[National implementation of HEARTS in Cuba: Management and innovation in a context of limited resourcesImplementação nacional da iniciativa HEARTS em Cuba: gestão e inovação em um contexto de recursos limitados]. [PDF]

Rev Panam Salud Publica
Valdés González Y, Tamayo Muñiz S, Rodríguez Salvá A, Díaz Piñera A, Derivet Thaureaux D, Pérez Leyva ME, Pomares Y, Antonio González M, Rodríguez L, Londoño E.   +9 more
europepmc   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Costs and impact of the Malaria Eradication Campaign in Colombia, 1957-1969 [PDF]

Biomedica
Padilla-Rodríguez JC, Olivera MJ.
europepmc   +1 more source

Línea norte : lote de “San Luis”, propiedad de los Ferrocarriles Nacionales

, 1944
Plano, Dimensión : 40 x 100 cm. ; Escala : 1:2000Plano topográfico. Contiene ilustraciones sobre el lote propiedad de los Ferrocarriles Nacionales.

core  

Highly‐Time‐Resolved Measurements of Tryptophan's Distribution and Homeostatic Regulation in Live, Intact Animals

Advanced Science, EarlyView.
Using a novel, aptamer‐based biosensor, here we have performed 20‐s‐resolved, in situ measurements of plasma‐free tryptophan in the jugular veins of live rats (blue). This unprecedented time‐resolution provides insights into the regulation of tryptophan metabolism in live, intact animals.
Yuyang Wu, Chelsea N. Brown, Zeki Duman, Rose Mery Bakestani, Carl M. Kirkpatrick, Joao Hespanha, Tod Kippin, Kevin W. Plaxco   +7 more
wiley   +1 more source