Results 211 to 220 of about 461,960 (292)

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

open access: yesAdvanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau   +3 more
wiley   +1 more source

Targeting Mitochondrial Redox Signaling Promotes Neuroregeneration and Functional Recovery in a Multiple Sclerosis Model

open access: yesAdvanced Science, EarlyView.
Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima   +18 more
wiley   +1 more source

A Transcriptionally Distinct Intermediate Activation State Precedes Langerhans Cell Migration From the Epidermis

open access: yesAdvanced Science, EarlyView.
A transcriptionally distinct intermediate Langerhans cell state is identified between steady and migratory populations during skin injury. Integrated single‐cell transcriptomics, flow cytometry, and intravital imaging reveal state‐specific markers and implicate complement signaling, particularly C3, in regulating Langerhans cell accumulation near ...
Artem Kiselev   +5 more
wiley   +1 more source

[Performance of prognostic scores during the first and second waves of COVID-19 pneumonia] [PDF]

open access: yesRev Fac Cien Med Univ Nac Cordoba
Reyna SMT   +18 more
europepmc   +1 more source

EZpred: Improving Deep Learning‐Based Enzyme Function Prediction Using Unlabeled Sequence Homologs

open access: yesAdvanced Science, EarlyView.
Schematic of the EZpred pipeline, which provides high‐confidence predictions of enzyme function using a combination of sequence alignments, structural alignments, and deep learning. EZpred can be used to provide substantial increases in the richness of protein function annotations at genomic scales.
Chengxin Zhang   +2 more
wiley   +1 more source

Current Standards of Monitoring Models in Healthcare Settings

open access: yesAdvanced Intelligent Discovery, EarlyView.
AI/ML‐enabled medical devices are entering clinical practice faster than monitoring standards mature. This review highlights gaps in postmarket surveillance, limited use of predetermined change‐control plans, and the need for ongoing performance tracking, drift detection, explainability, and workflow‐aware governance to support safer, more reliable ...
Alan Kay   +5 more
wiley   +1 more source

Los indígenas y sus lenguas en los informes de los Inspectores de Territorios Nacionales (1890-1916)

open access: yes
Fil: Hidalgo Martínez, Santiago Martín. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
openaire   +1 more source

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