Results 21 to 30 of about 1,273,386 (242)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

High discrimination infrared polarimetry via intrinsic anisotropic photogating in black phosphorus meta-polarization detectors

Nature Communications
Filterless miniaturized polarization photodetectors are essential for next-generation ultracompact optical and optoelectronic systems. However, achieving high polarization discrimination and high sensitivity over a broad wavelength range based on a ...
Yonghao Bu, Tao Ye, Ruowen Wang, Jing Zhou, Jie Deng, Yuran Zhen, Mengdie Shi, Wenji Jing, Rui Xin, Yujie Zhang, Junwei Huang, Tianxin Li, Wei Lu, Xiaoshuang Chen   +13 more
doaj   +1 more source

How to characterize figures of merit of two-dimensional photodetectors

Nature Communications, 2023
Photodetectors based on two-dimensional (2D) materials have been the focus of intensive research and development over the past decade. However, a gap has long persisted between fundamental research and mature applications.
Fang Wang, Tao Zhang, Runzhang Xie, Zhen Wang, Weida Hu   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Infrared fibres in astronomical instrumentation [PDF]

, 1995
For several years multi-object spectroscopy systems have been available for carrying out survey work in the visible region, but until very recently there has not been a system for the near infrared region.
Haynes, Roger
core  

Motion Artifact Reduction in Breast Dynamic Infrared Imaging [PDF]

, 2009
Dynamic infrared imaging is a promising technique in breast oncology. In this study a QWIP infrared camera is used to acquire a sequence of consecutive thermal images of the patient's breast for 10 s.
Molinari, Filippo, Knaflitz, Marco, Agostini, Valentina   +2 more
core   +1 more source

Mid-infrared femtosecond laser-induced damages in As2S3 and As2Se3 chalcogenide glasses

Scientific Reports, 2017
In this paper, we report the first measurements of mid-infrared (MIR) femtosecond laser-induced damage in two typical chalcogenide glasses, As2S3 and As2Se3.
Chenyang You, Shixun Dai, Peiqing Zhang, Yinsheng Xu, Yingying Wang, Dong Xu, Rongping Wang   +6 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Retrieval of Carbon Monoxide Vertical Column Densities from SCIAMACHY Infrared Nadir Observations [PDF]

, 2008
Nadir observations in the shortwave infrared channels of SCIAMACHY onboard the ENVISAT satellite can be used to derive information on CO, CH4, N2O, CO2, and H2O.
Doicu, Adrian, Franz Schreier, Gimeno-Garcia, Sebastian, Hess, Michael, A. Doicu, Schreier, Franz, Lichtenberg, Günter, G. Lichtenberg, Sebastián Gimeno‐García, M. Hess   +9 more
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source