Results 61 to 70 of about 879,641 (305)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Spatial Analysis of Asymmetry in the Development of Tourism Infrastructure in the Borderlands: The Case of the Bystrzyckie and Orlickie Mountains

open access: yesISPRS International Journal of Geo-Information, 2020
This paper discusses the issue of analyzing the development of cross-border tourism infrastructure in the borderlands of countries with diversified administrative divisions and spatial databases, which hinders the use of national statistical units for ...
Michalina Jędruch   +2 more
doaj   +1 more source

Seismic Response to Injection Well Stimulation in a High-Temperature, High-Permeability Reservoir [PDF]

open access: yes, 2019
Fluid injection into the Earth's crust can induce seismic events that cause damage to local infrastructure but also offer valuable insight into seismogenesis.
Chet Hopp   +9 more
core   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Towards a sustainable Growth story: A critical analysis of the fundamentals [PDF]

open access: yes, 2008
In this paper, I will develop an insight into the growth process of Indian Economy and will find that increased inequality due to unconventional transitions have its negative implications for future growth prospects and the overall issue of ...
Saraswat, Deepak
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Taxation, infrastructure, and endogenous trade costs in New Economic Geography [PDF]

open access: yes
This paper presents a New Economic Geography model with distortionary taxation and endogenized trade costs. Tax revenues finance a public good, infrastructure.
Gruber, Stefan, Marattin, Luigi
core   +1 more source

A Sharing- and Competition-Aware Framework for Cellular Network Evolution Planning [PDF]

open access: yes, 2015
Mobile network operators are facing the difficult task of significantly increasing capacity to meet projected demand while keeping CAPEX and OPEX down. We argue that infrastructure sharing is a key consideration in operators' planning of the evolution of
DaSilva, Luiz A.   +3 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Performance Index Model of Raw Water Infrastructure

open access: yesCivil Engineering Journal
This research intends to build a performance index model of raw water infrastructure mathematically by considering technical, non-technical, and environmental aspects. The research location is in Lombok and the Sumbawa Islands. Data is collected by field surveys and questionnaires that are distributed to 160 respondents related to raw water ...
Sri U. Sudiarti   +3 more
openaire   +1 more source

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