Results 61 to 70 of about 184,615 (303)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Spatial Analysis of Asymmetry in the Development of Tourism Infrastructure in the Borderlands: The Case of the Bystrzyckie and Orlickie Mountains

open access: yesISPRS International Journal of Geo-Information, 2020
This paper discusses the issue of analyzing the development of cross-border tourism infrastructure in the borderlands of countries with diversified administrative divisions and spatial databases, which hinders the use of national statistical units for ...
Michalina Jędruch   +2 more
doaj   +1 more source

SMIX Live -- A Self-Managing Index Infrastructure for Dynamic Workloads

open access: yes2012 IEEE 28th International Conference on Data Engineering, 2012
As databases accumulate growing amounts of data at an increasing rate, adaptive indexing becomes more and more important. At the same time, applications and their use get more agile and flexible, resulting in less steady and less predictable workload characteristics.
Thomas Kissinger   +2 more
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Decomposing generalized transport costs using index numbers: A geographical analysis of economic and infrastructure fundamentals [PDF]

open access: yes
We use the economic theory approach to index numbers in order to improve the existing definitions and decompositions of generalized transport costs (GTCs), and thus to obtain a better understanding of their economic and infrastructure determinants. Using
Zofío, José Luis   +3 more
core  

Culture in sustainable infrastructure [PDF]

open access: yes, 2011
The high failure rate of infrastructures around the world is alarming, most especially when such failures constrain economic growth and development.
Alohan Omoregie   +3 more
core   +1 more source

Evaluation index system of public charging infrastructure.

open access: yes, 2021
Evaluation index system of public charging infrastructure.
Kun Yang (19445), Hua Dong (241097)
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Infrastructure and growth in Africa [PDF]

open access: yes
The goal of the paper is to provide a comprehensive assessment of the impact of infrastructure development on growth in African countries. Based on econometric estimates for a sample of 136 countries from 1960-2005, the authors evaluate the impact on per
Calderon, Cesar
core  

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