Results 111 to 120 of about 267,567 (250)
Advanced Robotics Research, EarlyView.Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin +3 more
wiley +1 more source
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans
Advanced Science, EarlyView.This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao +19 more
wiley +1 more source
Ciência Animal Brasileira, 2010 A manutenção da pressão arterial, no transanestésico, consiste grande desafio, principalmente quando se trata da espécie equina, suscetível à instabilidade cardiovascular. Por isso, torna-se imperioso utilizar técnica anestésica que mantenham estáveis os
José Henrique Saraiva Borges +5 more
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Advanced Science, EarlyView.ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source
"La colecistectomía laparoscópica se considera el estándar de oro para el tratamiento quirúrgico de la enfermedad de la vesícula biliar debido a su carácter mínimamente invasivo y los mejores resultados clínicos.
Estrada Vallejo, Javier Edmundo
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Sedoanalgesia, hemodinamia y efectos adversos de remifentanilo en infusión continua con bomba y microgoteo para legrado uterino [PDF]
, 2009 Compara la calidad de la sedo-analgesia, hemodinámica y los efectos adversos en la sedo analgesia con Remifentanilo en infusión continua con bomba y en microgoteo. Longitudinal, prospectivo, comparativo y cuasi experimental.
Arizabal Espinoza, María Teresa
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Advanced Science, EarlyView.The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang +11 more
wiley +1 more source
Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions
Advanced Science, EarlyView.Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han +11 more
wiley +1 more source
Evaluación del protocolo de infusión continua de insulina en pacientes del Servicio de Cuidados Intensivos del Hospital Alberto Sabogal Sologuren [PDF]
, 2009 El documento digital no refiere asesorPropósito: el paciente en estado crítico presenta con frecuencia hiperglicemia, de origen multifactorial. Este estado puede empeorar la evolución del paciente crítico, para ello existen muchas estrategias para ...
Silva Teran, Joel Jair
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