Results 171 to 180 of about 1,252 (212)

Navigating Asparaginase Treatment for Patients With Acute Lymphoblastic Leukemia: US Consensus Panel Recommendations on the Role of Multidisciplinary Care

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Asparaginase is a critical treatment component for patients with acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL). However, the successful delivery of asparaginase‐based therapy remains challenging across care settings due to its complex administration, distinct toxicity profile, prolonged treatment duration, and the need for ...
Amir Ali   +8 more
wiley   +1 more source

Ionic Liquid Electrolytes for Extreme Temperature Conditions: Challenges and Perspective

open access: yesAngewandte Chemie, EarlyView.
Ionic liquids (ILs) have gained great attention as safe electrolyte components in recent years. This review elucidates the temperature effects on IL‐based electrolytes from molecular configurations, physicochemical properties, and interfacial chemistry, raises the challenges and design strategies operating at low‐ and HT, providing valuable guidance ...
En Xie   +11 more
wiley   +2 more sources

Regional gas exchange evaluation during ex vivo lung perfusion in a swine model of localized lung dysfunction

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Abstract Background Ex vivo lung perfusion (EVLP) allows the evaluation of lungs that do not meet standard transplantation criteria. Current procedures do not permit the identification of regional functional deficits. We investigated the feasibility of assessing lobar gas exchange during EVLP in a swine model.
Giulia Maria Ruggeri   +16 more
wiley   +1 more source

Hyperglycemia-induced isolated aphasic status epilepticus a case-report and literature review. [PDF]

open access: yesDement Neuropsychol
Khieukhajee J   +3 more
europepmc   +1 more source

Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo   +13 more
wiley   +1 more source

Cooling Holes in Polymer Spur Gears: A Critical Analysis of Heat Dissipation Benefits and Mesh Stiffness Penalties

open access: yesJournal of Applied Polymer Science, EarlyView.
Cooling holes provide a simple passive cooling strategy for polymer spur gears, reducing maximum operating temperature by up to 9.39% while introducing a measurable gear mesh stiffness penalty. A validated response‐surface model reveals how hole size and location govern this thermal–mechanical trade‐off, enabling design optimization for thermally and ...
Abderrahim Baccar   +5 more
wiley   +1 more source

Compositional Time–Temperature–Transformation and Post‐Processing Window Mapping of Epoxy Nanocomposites via Machine Learning

open access: yesJournal of Applied Polymer Science, EarlyView.
Discrete DSC and rheological data are transformed into continuous compositional Time–temperature–transformation (TTT) diagrams through physics‐informed Gaussian Process Regression. The proposed framework quantitatively predicts post‐gel processing windows across temperature and nanofiller composition, providing a practical route for accelerated design ...
Otávio Bianchi   +6 more
wiley   +1 more source

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