Results 191 to 200 of about 21,563 (293)

DADA Enhances CD8+ T Cell Stemness to Improve Anti‐Tumor Immunity and Immunotherapy Efficacy

Advanced Science, EarlyView.
Diisopropylamine dichloroacetate (DADA) enhances CD8+ T cell stemness by improving OXPHOS and mitochondrial fitness in a PDK1‐depenpendent manner. This metabolic shift strengthens CD8+ T cell anti‐tumor immunity, improves responses to PD‐1 blockade, and endows CAR‐T cells with prolonged persistence and resistance to terminal exhaustion, highlighting a ...
Mingyue Bi, Fei Li, Heng Jiang, Lingling Gu, Mengjie Sun, Kunyu Lu, Pianpian Liu, Ruyue Xie, Wenqiang Ma, Meijuan Zheng, Xianwei Wang, Xuefu Wang, Jingjing Cong   +12 more
wiley   +1 more source

[Experience with medical treatment using sirolimus for cardiac rhabdomyomas in children. A case series]. [PDF]

Arch Cardiol Mex
Stelmaszewski EV, Olivetti ME, Diez-Mori F, Salgado G.   +3 more
europepmc   +1 more source

Control del dolor postoperatorio en hemorroidectomía ambulatoria mediante infusión endovenosa continua domiciliaria

, 2005
J. Recasens, S. Boada, Rita Puig, Christian Ferrer, Paz Sáenz de Jubera, M. Rull   +5 more
openalex   +1 more source

Manejo de la vía subcutánea y uso de bombas de infusión continua en PADES 2016

, 2017
Elena Codina-Casanovas
openalex   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Acrodermatitis continua of Hallopeau: a review and update on biological and small molecule targeted immunomodulatory therapies. [PDF]

Front Immunol
Sun Q, Han L, Lin Z, Wu Y, Li C, Ying Z, Zhao Z.   +6 more
europepmc   +1 more source

Deformation Driven Suction Cups: A Mechanics‐Based Approach to Wearable Electronics

Advanced Science, EarlyView.
Deformation‐driven suction cups enable robust, reversible adhesion of wearable electronics to human skin spanning wide mechanical compliance, without adhesives or tight straps. By integrating mechanics modeling, experiments, and contact mechanics theory, this work reveals how cup geometry, substrate compliance, and interfacial adhesion govern suction ...
Seola Lee, Andrew Akerson, Roham Pardakhtim, Ehsan Hajiesmaili, Kevin Rhodes, Zidong Li, Andrew Stanley, Amirhossein Amini, Daniele Piazza, Chiara Daraio, Tianshu Liu   +10 more
wiley   +1 more source

The B-Health Box: A Standards-Based Fog IoT Gateway for Interoperable Health and Wellbeing Data Collection. [PDF]

Sensors (Basel)
Marques M, Delgado-Gomes V, Januário F, Lopes C, Jardim-Goncalves R, Agostinho C.   +5 more
europepmc   +1 more source

Trackable Tolerogenic Macrophages Integrate PD‐L1 and Rapamycin Signaling to Suppress Alloimmune Responses in Transplantation

Advanced Science, EarlyView.
We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang, Yuan Song, Yuji Xie, Junmin Zhang, Jing Liu, Wenyuan Wang, Ying Xu, Wenqian Wu, Wuqi Zhou, Qiaofeng Jin, Jing Wang, Yali Yang, Li Zhang, Tang Gao, Mingxing Xie   +14 more
wiley   +1 more source

Unveiling epilepsia partialis continua as an early indicator of HIV encephalitis. [PDF]

Indian J Sex Transm Dis AIDS
Arivalagan B, Goel J, Gupta S, Singh BP, Bhardwaj S, Rayapureddi K.   +5 more
europepmc   +1 more source