Results 131 to 140 of about 759,358 (315)

Safe and tolerable one-hour pamidronate infusion for multiple myeloma patients

, 2008
Dimitrios Chantzichristos, Andréasson Björn, Johansson PeterDepartment of Internal Medicine, Uddevalla Hospital, Uddevalla, SwedenBackground: Once a month, patients with multiple myeloma received an infusion of bisphosphonates ...
Andréasson Björn, Dimitrios Chantzichristos, Johansson Peter   +2 more
core  

Antioxidant activity and physicochemical kinetics of a compounded spirit infused with Calophyllum brasiliense seeds

Cogent Food & Agriculture
The rising demand for alcoholic beverages with functional properties and distinct sensory profiles has driven innovation in the use of bioactive plant materials.
Nádson Líbio Beserra Ferreira, Flávio Luís Schmidt   +1 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Evaluation of Patient Satisfaction, Preference and Side Effects after Annual Zoledronic Acid Infusion in Patients with Osteoporosis

, 2017
Objective: In this study it was aimed to evaluate the patient satisfaction, therapy preference and side-effect profile in patients who receive annual zoledronic acid (ZA) infusion.
Selmin Gülbahar, Banu Dilek, Didem Erdem, ŞAHİN, EBRU, DİLEK, BANU, Erdem, Didem, Ebru Şahin, GÜLBAHAR, SELMİN, Bulut, Deniz, Deniz Bulut   +9 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Thiopentone infusions [PDF]

Anaesthesia, 1980
M, Helliwell, R J, Flanagan
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Constant plasma volume and colloid osmotic pressure after infusion of albumin 20%: A secondary analysis

Physiological Reports
Aberrant elimination patterns after intravenous infusion of albumin 20% may predispose to persistent vascular overload or hyper‐oncoticity. In the present report, the frequency of deviating elimination patterns was studied by visual examination followed ...
Robert G. Hahn
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Hepatic arterial infusion chemotherapy for liver metastases from gastric cancer: an analysis in western patients

, 2011
The advantage of administering chemotherapy by hepatic arterial infusion is the achievement of high drug concentrations in the liver. Oxaliplatin, irinotecan and 5-flourouracil are active agents in advanced gastric cancer.
Schaefer, C., Guido Schumacher, Bernhard Gebauer, Floercken, A., Bernd Dörken, Breithaupt, K., Dogan, Y., Doerken, B., Dmitry Bichev, Riess, H., Yasemin Dogan, Bichev, D., Thuss-Patience, P.C., Schumacher, G., Hanno Riess, Kirstin Breithaupt, Anne Flörcken, Peter C Thuss-Patience, Gebauer, B., Claudia Schaefer   +19 more
core   +1 more source