Results 141 to 150 of about 1,577,244 (363)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Peripheral Infusion of IGF-I Selectively Induces Neurogenesis in the Adult Rat Hippocampus
Journal of Neuroscience, 2000 In several species, including humans, the dentate granule cell layer (GCL) of the hippocampus exhibits neurogenesis throughout adult life. The ability to regulate adult neurogenesis pharmacologically may be of therapeutic value as a mechanism for ...
M. Åberg +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Performance testing carried out in the development of the prototype zero-g fluid infusion system is described and summarized. Engineering tests were performed in the course of development, both on the original breadboard device and on the prototype ...
core +1 more source
Risk factors and prevention strategies for mastitis in New Zealand dairy heifers : this thesis is completed as a partial requirement for the Masters of Veterinary Studies (Epidemiology) from Massey University, Palmerston North, New Zealand [PDF]
, 2006 The aims of this thesis were to investigate herd level risk factors for heifer clinical mastitis and to test the efficacy of a pre-calving intervention on prevalence of post-calving IMI, incidence of clinical mastitis and somatic cell count (SCC) in ...
Parker, Katrina Ivy
core
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
International Review of Research in Open and Distributed Learning, 2003 This article seeks to identify critical success factors for the appropriate infusion of instructional technologies to advance open learning in higher education within developing settings.
Philip M. Uys
doaj
Challenges and Opportunities in Drug Administration: The Twelve Tasks of Infusorix!
Pharmaceutical Technology in Hospital Pharmacy, 2017 The objective of this paper was to present 12 examples of the challenges of parenteral drug administration that hospital pharmacists and other clinicians face. These examples were presented as part of a talk during the International Symposium on Infusion
Bussières Jean-François
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source