Results 81 to 90 of about 165,534 (345)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

The administration of immune checkpoint inhibitors via an elastomeric pump versus conventional intravenous infusion: an economic perspective

BMC Health Services Research
Background Recent studies have underscored the potential of innovative administration methods to mitigate the capacity burden on healthcare systems, without compromising the quality of care.
Michiel Zietse, Ruben Malmberg, Roelof W.F. van Leeuwen, Frederick W. Thielen, Carin A. Uyl – de Groot   +4 more
doaj   +1 more source

Anesthesia and analgesia in oncogynecology

Опухоли женской репродуктивной системы, 2014
Surgical treatment may be of poor quality due to the fact that an anesthesiologist is unaware of the possible scope of surgery and a surgeon is unaware of different modes of analgesia.
R. V. Garyaev
doaj   +1 more source

Is Hepatic Artery Infusion Pump Therapy a New Bridging Strategy to Liver Transplant for Advanced Liver Malignancy? [PDF]

, 2023
Jin He, Andrew M. Cameron
openalex   +1 more source

Medical Cyber-Physical Systems Development: A Forensics-Driven Approach

, 2017
The synthesis of technology and the medical industry has partly contributed to the increasing interest in Medical Cyber-Physical Systems (MCPS). While these systems provide benefits to patients and professionals, they also introduce new attack vectors ...
Choo, Kim-Kwang Raymond, Glisson, William Bradley, Grispos, George   +2 more
core   +1 more source

EFFECTS OF INSULIN, GLUCAGON, AND INSULIN/GLUCAGON INFUSIONS ON LIVER MORPHOLOGY AND CELL DIVISION AFTER COMPLETE PORTACAVAL SHUNT IN DOGS [PDF]

, 1976
Insulin, glucagon, and insulin/glucagon mixtures have been infused for four days into the left portal vein of dogs after portacaval shunt. In the left but not the right liver lobes, insulin alone reduced atrophy, preserved hepatocyte ultrastructure, and ...
Blackard, Bollman, Bucher, Child, Eck, Felig, Felig, Field, Fisher, Fisher, Hahn, Holley, Izzo, Leffert, Loud, Madison, Mann, Marchioro, Marchioro, Marchioro, Meyer, Popper, Reaven, Rous, Rubin, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Tchobroutsky, Warren, Wembren, Younger   +36 more
core   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Intraspinal Drug Delivery Reservoir Refill Procedure by Non-Physician Clinicians: A Nation-Wide Survey of Training, Pocket Fill Experience, and Life-Long Learning Behaviors [PDF]

, 2016
Intraspinal drug delivery (IDD) is a safe and efficacious method used to deliver medications for the treatment of chronic neurologic disease that requires periodic reservoir refills that can place patients at risk for a rare, accidental but potentially ...
McGlothlen, Gail
core   +1 more source

Optimal Regulation of Blood Glucose Level in Type I Diabetes using Insulin and Glucagon

, 2019
The Glucose-Insulin-Glucagon nonlinear model [1-4] accurately describes how the body responds to exogenously supplied insulin and glucagon in patients affected by Type I diabetes.
Della Rossa, Fabio, Klickstein, Isaac, Russell, John, Shirin, Afroza, Sorrentino, Francesco   +4 more
core   +4 more sources

Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice [PDF]

, 2015
Mice exposed to standard (SE) or enriched environment (EE) were transplanted with murine or human glioma cells and differences in tumour development were evaluated.
BENIGNI, GIORGIA, BERNARDINI, Giovanni, Brau, Frederic, CHECE, Giuseppina, D'ALESSANDRO, GIUSEPPINA, ESPOSITO, Vincenzo, GAROFALO, STEFANO, LAURO, CLOTILDE, LIMATOLA, Cristina, MAGGI, Laura, MAINIERO, Fabrizio, PORZIA, Alessandra, ROSA, ALESSANDRO, SANTONI, Angela   +13 more
core   +1 more source