Results 221 to 230 of about 5,157 (281)

PROTRACTED PARENTERAL DRUG INFUSION IN AMBULATORY SUBJECTS USING AN IMPLANTABLE INFUSION PUMP

ASAIO Journal, 1977
This study demonstrates the feasibility of ambulatory heparin therapy and its potential for successful treatment of refractory thromboembolic disease. The proven capability of the implantable infusion pump to provide long-term heparin infusion in ambulatory subjects suggests that it may have application in the delivery of other parenteral drugs as well.
T D, Rohde, P J, Blackshear, R L, Varco, H, Buchwald   +3 more
openaire   +2 more sources

[40] Implantable infusion pumps: Practical aspects

1985
Publisher Summary This chapter discusses the practical aspects of implantable infusion pumps. The chapter discusses the pump implantation in humans. As with the implantation of any foreign body, the development of an infection at the site of infusion pump implantation usually requires pump removal.
Perry J. Blackshear, Bruce D. Wigness, Anne M. Roussell, Alfred M. Cohen   +3 more
openaire   +1 more source

Regional hepatic chemotherapy using an implantable drug infusion pump

The American Journal of Surgery, 1983
Regional infusion of chemotherapeutic agents in the treatment of liver cancer can greatly increase tumor exposure to certain drugs. Exposure is 100 times greater with floxuridine, 6 times greater with mitomycin C, and 6 times greater with BCNU. The Model 400 Infusaid implantable, refillable drug infusion pump overcomes much of the discomfort and ...
A M, Cohen, S D, Kaufman, W C, Wood, A J, Greenfield   +3 more
openaire   +2 more sources

Transbrachial hepatic arterial chemotherapy using an implanted infusion pump

Diseases of the Colon & Rectum, 1980
Two patients with hepatic metastases from colonic cancer were treated with hepatic arterial FUDR using an innovative drug infusion system. The two patients reported underwent transbrachial hepatic artery catheterization with a 5 French polyethylene catheter.
A M, Cohen, W C, Wood, A, Greenfield, A, Waltman, C, Dedrick, P J, Blackshear   +5 more
openaire   +2 more sources

A complication of the implantable constant infusion chemotherapy pump

Journal of Surgical Oncology, 1984
AbstractThe treatment of metastatic colorectal cancer to the liver has been a significant problem for clinicians in the past. Recent technical advances in infusion systems in the form of the infusaid pump has allowed delivery of chemotherapeutic agents to the liver with great reliability.
openaire   +2 more sources

Continuous infusion with implantable pumps: expanding the radiologist's role

European Journal of Radiology, 1991
Drug infusion systems attract increasing attention as biomedical technology offers miniaturized devices for targeted delivery of therapeutic substances on an outpatient basis. We have used a totally implantable, subcutaneous pump, externally programmable by radiofrequency link, learning the technique of implantation and management and using various ...
B, Damascelli, M G, Bonalumi, A, Marchianò, C, Spreafico, F, Garbagnati, A, Amadeo, M, Salvetti, L F, Frigerio, G, Piragine, A, Cesa Bianchi   +9 more
openaire   +2 more sources

External and Implanted Pumps for Apomorphine Infusion in Parkinsonism

1993
Continuous delivery of dopaminergic agents to the striatum is a major challenge to improve the treatment of Parkinson's disease. Apomorphine is one of the best candidates because of its solubility and its D1 and D2 receptor agonist properties. Seventeen Parkinsonian patients suffering from severe L-dopa-induced on-off effects were treated by continuous
P, Pollak, A L, Benabid, P, Limousin, C L, Gervason, E, Jeanneau-Nicolle   +4 more
openaire   +2 more sources

A new spring-driven implantable drug infusion pump

Images of the Twenty-First Century. Proceedings of the Annual International Engineering in Medicine and Biology Society, 2003
An implantable infusion pump which uses elastomer spring pressure to provide constant-rate drug delivery is described. Desirable features of the design are its low-cost construction, temperature and pressure insensitivity, high volumetric efficiency, and scale flexibility. Test results for prototype models are reported.
F.D. Dorman, B.D. Wigness, T.D. Rohde, W.L. Beling, H. Buchwald   +4 more
openaire   +1 more source

Outpatient Dobutamine Infusion Using a Totally Implantable Infusion Pump for Refractory Congestive Heart Failure

Chest, 1985
A patient with refractory congestive heart failure was treated, on an outpatient basis, with intermittent dobutamine using a totally implantable infusion pump. Dobutamine was infused for 48 hours every week and resulted in sustained clinical improvement.
M, Berger, C K, McSherry
openaire   +2 more sources

Continuous Intraperitoneal Insulin Infusion from Implantable Pumps

2014
Continuous intraperitoneal insulin infusion (CIPII) presents specific pharmacokinetics and pharmacodynamics which allow insulin replacement in a way closer to physiology than subcutaneous insulin delivery. Insulin absorption occurs faster, mainly in the hepatic venous portal system, which results in lower peripheral insulin levels.
openaire   +1 more source