Results 191 to 200 of about 63,253 (224)

IL‐33‐Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1‐IGF2R Axis in Ankylosing Spondylitis

Advanced Science, EarlyView.
This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao, Siwen Chen, Hua Chao, Zihao Li, Hao Yang, Dongying Chen, Sifang Li, Shuai Zhang, Jingyu Zhang, Jianru Wang, Zemin Li, Xiang Li, Zhongping Zhan, Tangming Guan, Yiwen Zhang, Wende Li, Hui Liu   +16 more
wiley   +1 more source

Management of anesthesia in a child with mitochondrial disease for dental rehabilitation. [PDF]

J Anaesthesiol Clin Pharmacol
Bhuyan M, Rajan S, Atri P, Paul J.
europepmc   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

Anaesthesia in chronic dialysis patients: A narrative review. [PDF]

World J Crit Care Med
Yaxley J.
europepmc   +1 more source

Neoadjuvant Chemotherapy With Cisplatin Up‐Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14‐Mediated EMT Activation

Advanced Science, EarlyView.
Oral squamous cell carcinoma cells exhibit upregulated expression of GSDMD upon exposure to low‐dose cisplatin chemotherapy, which subsequently interacts with MMP14 through its N‐terminal domain, activating the epithelial‒mesenchymal transition (EMT) process and promoting the lymph node metastasis of oral squamous cell carcinoma.
Zixian Huang, Qiming Jiang, Qianyu Zhang, Nan Lu, Xi Rui, Rui Chen, Yan Wang, Yuepeng Wang, Xiaoding Xu, Zhiquan Huang   +9 more
wiley   +1 more source

Application of a multifunctional chemotherapy infusion device for reducing antineoplastic drug extravasation. [PDF]

Front Oncol
Yang LH, Liu LP, Jiang FY, Huang FZ, Xie CF, Lin XQ, Wang P, Feng XL.   +7 more
europepmc   +1 more source

Lignin‐Based Photothermal Materials: Bridging Sustainability and High‐Efficiency Energy Conversion

Advanced Science, EarlyView.
This review provides new perspectives on lignin‐based photothermal materials, emphasizing their molecular structure for efficient energy conversion. It summarizes mechanisms and strategies for improving photothermal efficiency in applications of photothermal actuation, desalination, and biomedical therapies.
Zhiwen Sun, Changyou Shao, Sanwei Hao, Jifei Zhang, Wenfeng Ren, Bing Wang, Lingping Xiao, Hanhui Lei, Terence X. Liu, Zhanhui Yuan, Run‐cang Sun   +10 more
wiley   +1 more source

Hospitalizations for bronchiolitis among infants before and after the SARS-CoV-2 pandemic: an area-based study of the Emilia-Romagna Region, Italy. [PDF]

Ital J Pediatr
Ballardini E, Manfrini M, Fattori S, Pellacani E, Ćosić B, Gargano G, Berardi A.   +6 more
europepmc   +1 more source

Flexible Regulation of Optical Properties Based on Structure Size‐Driven Intermolecular Interactions for Phototherapy

Advanced Science, EarlyView.
Herein, ACQ@AIE bimolecular systems are developed by noncovalently combining an aggregated‐caused quenching (ACQ) molecule with three aggregated‐induced emission (AIE) molecules. Differentials in structural size drive different patterns of intermolecular interactions, leading to distinct and tunable optical properties.
Zhichao Gong, Guangbo Kang, Yu Cao, Jiachen Pan, Xuejiao Rong, Xiaobing Du, Danping Zhang, He Huang, Shuxian Meng   +8 more
wiley   +1 more source