Results 91 to 100 of about 655,159 (342)

Effects of cinnamon, thyme and turmeric infusions on the performance and immune response in of 1- to 21-day-old male broilers

, 2012
This study was conducted to investigate the effects of the replacement of drinking water by herb infusions on the performance, relative weight of internal organs, hematocrit and immune response to Newcastle disease virus of broiler chickens.
G. Sadeghi, A. Karimi, SH Padidar Jahromi, T. Azizi, A. Daneshmand   +4 more
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Validation of High-Performance Liquid Chromatography for determination and stability assessment of dobutamine hydrochloride in pediatric intravenous therapy

Evidência
Severely ill children and newborns typically require a wide range of intravenous medications as part of specific therapies tailored to their developmental and growth characteristics.
Tatiany Calegari , Fernando Fonseca, Beatriz Alves, Glaucia da Veiga, Paulo César Rosa , Mavilde Pedreira, Maria Angélica Peterlini   +6 more
doaj  

Effect of dural puncture epidural combined with programmed intermittent epidural bolus on labor analgesia in patients with gestational hypertension: a randomized controlled clinical trial

Frontiers in Medicine
BackgroundHypertensive disorders of pregnancy affect 5–10% of pregnancies and require the maintenance of hemodynamic stability while providing effective labor analgesia.
Binghui Zhang, Hongyang Zhang, Yuan Wu, Guofang Li, Shuxiang Liu, Kai Zhao   +5 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

HLA class II upregulation during viral infection leads to HLA-DP–directed graft-versus-host disease after CD4+ donor lymphocyte infusion [PDF]

, 2013
Sanja Stevanović, Cornelis A.M. van Bergen, Simone A.P. van Luxemburg-Heijs, Boris van der Zouwen, Ekaterina S. Jordanova, Alwine B. Kruisselbrink, Marian van de Meent, Jessica C. Harskamp, Frans H.J. Claas, Erik W.A. Marijt, Jaap Jan Zwaginga, Constantijn J.M. Halkes, Inge Jedema, Marieke Griffioen, J.H. Frederik Falkenburg   +14 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Microcosting Study of Rituximab Subcutaneous Injection Versus Intravenous Infusion [PDF]

, 2017
Jovan Mihajlović, P. Bax, Erwin van Breugel, Hedwig M. Blommestein, Mels Hoogendoorn, Wobbe Hospes, Maarten J. Postma   +6 more
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source