Results 91 to 100 of about 36,315 (252)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Repellents inhibit P450 enzymes in Stegomyia (Aedes) aegypti. [PDF]
, 2012 The primary defence against mosquitoes and other disease vectors is often the application of a repellent. Despite their common use, the mechanism(s) underlying the activity of repellents is not fully understood, with even the mode of action of DEET ...
Graham D Moores +28 more
core +1 more source
Frontiers in Veterinary ScienceIntroductionMedication error is a major cause of preventable harm in healthcare. Superficially, solutions to medication error appear simple, however medication administration often occurs during high-risk clinical scenarios, and under varied and ...
Matthew McMillan
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Intraparenchymal NGF Infusions Rescue Degenerating Cholinergic Neurons
, 2000 Nerve growth factor (NGF) exerts both trophic (cell survival) and tropic (axonal growth-promoting) effects on several neuronal populations. In particular, its robust ability to prevent lesion-induced and spontaneous age-related basal forebrain ...
Mark H. Tuszynski
core +1 more source
Ciencia y Enfermería, 2008 A rede endovenosa é urna das principáis vias para administração de quimioterápicos e requer um cuidado especial na prevenção de extravasamento. Este estudo tem como objetivo verificar a incidência de alterações locáis na rede venosa de individuos em ...
Paula Elaine Diniz dos Reis +3 more
doaj
Tibial osteomyelitis following intraosseous infusion: a case report
Acta Orthopaedica et Traumatologica Turcica, 2020 Fluids, medications, and blood products can be rapidly administered via intraosseous infusion under emergency conditions, particularly to pediatric patients aged from 0 to 2 years.
Ali Dogan +5 more
doaj
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Bisphosphonate infusions: patient preference, safety and clinic use
, 2004 Goals of workWe set out to assess the preference of patients with common cancers involving bone receiving intravenous bisphosphonate therapy for either pamidronate (P) or zoledronic acid (Z) and their preference for the location of the infusion (clinic ...
Lowe, S. +9 more
core +1 more source