Results 161 to 170 of about 135,337 (265)

Qualitative phytochemical profiling, antioxidant activity, and development of a water-in-oil cream containing combined oil and water infusions of frankincense resin (<i>Boswellia spp.</i>): a preliminary <i>in vitro</i> study. [PDF]

J Pharm Pharm Sci
Javed S, Salawi A, Moni SS, Ahsan W, Khuwaja G, Alam MS, Sivadasan D, Jabeen A, Aziabi MY, Suwaydi HM, Alajam TEM, Nammazi AYM, Kadumi NMA.   +12 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Safety assessment of intravenous immunoglobulins in pediatric population: A systematic review of adverse events. [PDF]

Medicine (Baltimore)
Altowairqi M, Kamal NM, Aljaber A, Alelyani AM, Alzaedi MA, Aljuaid SSS, Algethami AS, Oshi MAM, Soliman ASA.   +8 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Time-of-Day Immunotherapy Administration and Outcomes in Advanced Cancers: A Systematic Review and Meta-Analysis.

JAMA Netw Open
Inoue S, Tsuboi I, Miszczyk M, Miyajima K, Roessler N, Alfarhan AR, Katayama S, Karakiewicz PI, Araki M, Shariat SF.   +9 more
europepmc   +1 more source

Multiple autologous tumor-infiltrating lymphocyte (LM103 infusion) therapy combined with immune checkpoint inhibitor induces repeated tumor regression in a patient with aggressive mucosal melanoma: a case report and literature review. [PDF]

Front Oncol
Li F, Xu Y, Wang Y, Mu N, Liu M, Feng W, Xue Y, Wu S, Wang X, Lizee G, Ma C.   +10 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Time-of-day of first checkpoint inhibitor dose influences clinical outcomes and immune responses in hepatocellular carcinoma. [PDF]

J Immunother Cancer
Li HL, Charmsaz S, Reisman BJ, Hayek F, Brancati M, Leatherman JM, Pazzi C, Lee RP, Zhao X, Christenson E, Arif W, Hernandez J, Ellis C, Gross NE, Thoburn C, Chandler GS, Mohindra R, Bansal S, Tang L, Guha A, Dang CV, Zaidi N, Jaffee EM, Laheru D, Zabransky DJ, Barretti M, Ho WJ, Yarchoan M, Nakazawa M.   +28 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Which beta-lactam infusion strategy is superior in ICU pneumonia? A Bayesian network meta-analysis of continuous, extended, and intermittent approaches. [PDF]

Antimicrob Agents Chemother
Lai P-C, Huang Y-T.
europepmc   +1 more source