Results 171 to 180 of about 622,443 (310)

Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: a randomized controlled trial.

Journal of the American Medical Association (JAMA), 2007
J. Tardif, J. Grégoire, P. L’allier, R. Ibrahim, J. Lésperance, T. Heinonen, S. Kouz, C. Berry, R. Basser, M. Lavoie, M. Guertin, J. Rodés‐Cabau   +11 more
semanticscholar   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Effects of nicotinic receptor antagonism on nicotine and THC self-administration in a model of polysubstance use. [PDF]

Int J Neuropsychopharmacol
Torregrossa MM, Racic T, Baglot SL, Stringfield SJ, Hill MN, Sved A.   +5 more
europepmc   +1 more source

Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid‐refractory, grade III–IV acute graft‐versus‐host disease

British Journal of Haematology, 2013
L. Ball, M. Bernardo, H. Roelofs, M. Tol, B. Contoli, J. Zwaginga, M. Avanzini, A. Conforti, A. Bertaina, G. Giorgiani, C. M. Jol-van der Zijde, M. Zecca, K. Le Blanc, F. Frassoni, R. M. Egeler, W. Fibbe, A. Lankester, F. Locatelli   +17 more
semanticscholar   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Qualitative phytochemical profiling, antioxidant activity, and development of a water-in-oil cream containing combined oil and water infusions of frankincense resin (<i>Boswellia spp.</i>): a preliminary <i>in vitro</i> study. [PDF]

J Pharm Pharm Sci
Javed S, Salawi A, Moni SS, Ahsan W, Khuwaja G, Alam MS, Sivadasan D, Jabeen A, Aziabi MY, Suwaydi HM, Alajam TEM, Nammazi AYM, Kadumi NMA.   +12 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Safety assessment of intravenous immunoglobulins in pediatric population: A systematic review of adverse events. [PDF]

Medicine (Baltimore)
Altowairqi M, Kamal NM, Aljaber A, Alelyani AM, Alzaedi MA, Aljuaid SSS, Algethami AS, Oshi MAM, Soliman ASA.   +8 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Multiple autologous tumor-infiltrating lymphocyte (LM103 infusion) therapy combined with immune checkpoint inhibitor induces repeated tumor regression in a patient with aggressive mucosal melanoma: a case report and literature review. [PDF]

Front Oncol
Li F, Xu Y, Wang Y, Mu N, Liu M, Feng W, Xue Y, Wu S, Wang X, Lizee G, Ma C.   +10 more
europepmc   +1 more source