Results 11 to 20 of about 58,973,815 (170)

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy. [PDF]

Alzheimers Dement
Abstract INTRODUCTION A subset of Alzheimer's disease (AD) patients exhibits a procoagulant state that remains undiagnosed despite available treatments. We developed positron emission tomography (PET) strategies to in vivo detect cerebral microthrombi in TgCRND8 mice. METHODS PET was performed with a fibrin‐binding probe (FBP) in TgCRND8 and wild‐type
Ceron C, Casquero-Veiga M, Lamanna-Rama N, Fernández-Nueda I, Fernández-Pena A, Olazagoitia N, Sobrino G, Herraiz A, González MI, Muñoz-Hernando M, Ruperti-Repilado A, Romero-Sanz E, Morcillo MÁ, Pérez-Medina C, Moro MA, Villaverde G, Rubio J, Fernandez-Ferro J, Desco M, Herranz F, Salinas B, Fuster V, Cortes-Canteli M.   +22 more
europepmc   +2 more sources

Enzymatic Poly(gallic acid)-grafted L-Histidine Reduces Cell Inflammation and Oxidative Stress: In Silico and In Vitro Studies. [PDF]

Chem Biodivers
Microwave‐assisted grafting yields a PGAL–His conjugate with enhanced binding through electrostatic and hydrogen‐bond interactions. The material modulates THP‐1 macrophage response, reducing ROS production, pro‐inflammatory cytokines (IL‐6, IL‐1β, TNF‐α), and cell adhesion.
Hernández-Valencia CG, Serratos IN, Torre-Morales CM, Ortiz-Huidobro RI, Vázquez A, Pedraza-Chaverri J, Martínez-López V, Fernández-Torres J, Sánchez-Sánchez R, Zamudio-Cuevas Y, Gimeno M.   +10 more
europepmc   +2 more sources

Prolonged Release of IL-10 From Enzyme-Mediated Poly-l-(Tyrosine-co-Phenylalanine) Nanocrystals Enhances Stability and Modulates Inflammatory Responses. [PDF]

Biopolymers
Schematic representation of enzyme‐mediated peptide nanocrystal formation and IL‐10 encapsulation, providing stabilized and sustained cytokine delivery that modulates macrophage phenotype and reduces inflammatory responses. ABSTRACT Protease‐catalyzed synthesis of a peptide composed of l‐tyrosine and l‐phenylalanine (2.2:1 M ratio) was achieved in a ...
Landa-Tencle F, Hernández-Valencia CG, Guzmán-Lagunes F, Montiel C, Cuellar-Entenza Y, Guerrero-Sánchez C, Stumpf S, Hoeppener S, Schubert US, Zamudio-Cuevas Y, Sánchez-Sánchez R, Gimeno M.   +11 more
europepmc   +2 more sources

APLICACIONES DE MATERIALES MESOPOROSOS EN LA INGENIERÍA DEL TEJIDO ÓSEO

infoANALITÍCA, 2021
La ingeniería de tejidos se define como un área multidisciplinaria e interdisciplinaria cuya función principal es proponer soluciones novedosas que promuevan la regeneración o reemplazo de tejidos dañados.
Leglys Contreras-Vargas, Karem Noris-Suarez, Gema Gonzalez   +2 more
doaj   +1 more source

REGENERACIÓN DEL ÓRGANO CUTÁNEO MEDIANTE INGENIERÍA DE TEJIDOS

Momento, 2020
La ingeniería de tejidos es una ciencia que busca desarrollar sustitutos de tejido y órganos para mantener, restaurar o aumentar las funciones de sus contrapartes heridas o enfermas in vivo.
Mauricio Rojas, Daniel Solera, Carolina Herrera, José R. Vega-Baudrit   +3 more
doaj   +1 more source

Electrochemical and Electroconductive Behavior of Silk Fibroin Electrospun Membrane Coated with Gold or Silver Nanoparticles

Membranes, 2022
The surface modification of materials obtained from natural polymers, such as silk fibroin with metal nanoparticles that exhibit intrinsic electrical characteristics, allows the obtaining of biocomposite materials capable of favoring the propagation and ...
Wilson Agudelo, Yuliet Montoya, Alejandra Garcia-Garcia, Adriana Restrepo-Osorio, John Bustamante   +4 more
doaj   +1 more source

Evaluation of the chemical-enzymatic decellularization method for obtaining extracellular trachea matrixes in a porcine model

Iatreia, 2016
Introduction: Different diseases may affect the trachea and, therefore, the quality of life. Tissue engineering may be a therapeutic alternative for patients with such diseases, using decellularized trachea matrixes seeded with cells from the recipient ...
Morales-Valencia, Mariana, Patiño-Vargas, María Isabel, Correa-Londoño, Luis Alfonso, Restrepo-Múnera, Luz Marina   +3 more
doaj   +1 more source

Cell Therapy and Tissue Engineering Products for Chondral Knee Injuries

Revista Colombiana de Biotecnología, 2017
The articular cartilage is prone to suffer lesions of different etiology, being the articular cartilage lesions of the knee the most common. Although most conventional treatments reduce symptoms they lead to the production of fibrocartilage, which has ...
Adriana Flórez Cabrera, Martha Isabel González Duque, Marta Raquel Fontanlla   +2 more
doaj   +1 more source

Presentación

Tecnología en Marcha, 2015
La Ingeniería de Tejidos consiste en la reconstrucción de la estructura tridimensional y funcional de órganos y tejidos, utilizando materiales naturales o sintéticos.
Miguel Rojas-Chaves, Laura A. Calvo-Castro, Carolina Centeno-Cerdas, Maritza Guerrero-Barrantes, Silvana Alvarenga-Venutolo, Silvia E. Castro-Piedra, María Inés Chaves-Rodríguez, Andrea Ulloa-Fernández   +7 more
doaj   +1 more source

Desarrollo de armazones (scaffolds) biodegradables procesados por microondas para su aplicación en ingeniería de tejidos [PDF]

, 2011
Se desarrolló un nuevo proceso para la fabricación de armazones ("scaffolds") porosos para su aplicación en Ingeniería de Tejidos mediante una técnica de calentamiento por microondas.
Troncoso Heros, Omar Paúl
core   +2 more sources