Results 11 to 20 of about 7,078 (161)

GK-1 Improves the Immune Response Induced by Bone Marrow Dendritic Cells Loaded with MAGE-AX in Mice with Melanoma

Journal of Immunology Research, 2014
The aim of dendritic cell (DC) vaccination in cancer is to induce tumor-specific effector T cells that may reduce and control tumor mass. Immunostimulants that could drive a desired immune response are necessary to be found in order to generate a long ...
Gabriela Piñón-Zárate, Miguel Ángel Herrera-Enríquez, Beatriz Hernández-Téllez, Katia Jarquín-Yáñez, Andrés Eliú Castell-Rodríguez   +4 more
doaj   +2 more sources

An in vitro study of ApxI from Actinobacillus pleuropneumoniae serotype 10 and induction of NLRP3 inflammasome-dependent cell death. [PDF]

Vet Rec Open, 2021
Abstract Background Actinobacillus pleuropneumoniae (AP) is the causative agent of porcine pleuropneumonia. Apx exotoxins are the most important virulence factors associated with the induction of lesions. ApxI is highly cytotoxic on a wide range of cells.
Hernandez-Cuellar E, Guerrero-Barrera AL, Avelar-Gonzalez FJ, Díaz JM, Chávez-Reyes J, Salazar de Santiago A.   +5 more
europepmc   +2 more sources

Mesenchymal stromal cells in human immunodeficiency virus-infected patients with discordant immune response: Early results of a phase I/II clinical trial. [PDF]

Stem Cells Transl Med, 2021
Between 15%‐30% of HIV‐infected subjects, do not achieve a significant immune recovery despite continuous viral suppression (immunological non‐responders). These subjects have an aberrant state of immune activation and inflammation. The treatment with adipose tissue allogeneic adult mesenchymal stromal cells does not neither improve immune recovery ...
Trujillo-Rodríguez M, Viciana P, Rivas-Jeremías I, Álvarez-Ríos AI, Ruiz-García A, Espinosa-Ibáñez O, Arias-Santiago S, Martínez-Atienza J, Mata R, Fernández-López O, Ruiz-Mateos E, Gutiérrez-Valencia A, López-Cortés LF.   +12 more
europepmc   +2 more sources

Unveiling the value of C-reactive protein as a severity biomarker and the IL4/IL13 pathway as a therapeutic target in recessive dystrophic epidermolysis bullosa: A multiparametric cross-sectional study. [PDF]

Exp Dermatol
Abstract Patients with recessive dystrophic epidermolysis bullosa (RDEB) experience numerous complications, which are exacerbated by inflammatory dysregulation and infection. Understanding the immunological mechanisms is crucial for selecting medications that balance inflammation control and immunocompetence.
Quintana-Castanedo L, Sánchez-Ramón S, Maseda R, Illera N, Pérez-Conde I, Molero-Luis M, Butta N, Arias-Salgado EG, Monzón-Manzano E, Zuluaga P, Martínez-Santamaría L, Fernández-Arquero M, Llames SG, Meana Á, de Lucas R, Del Río M, Vicente Á, Escámez MJ, Sacedón R.   +18 more
europepmc   +2 more sources

Successful development and clinical translation of a novel anterior lamellar artificial cornea. [PDF]

J Tissue Eng Regen Med, 2019
Abstract Blindness due to corneal diseases is a common pathology affecting up to 23 million individuals worldwide. The tissue‐engineered anterior human cornea, which is currently being tested in a Phase I/II clinical trial to treat severe corneal trophic ulcers with preliminary good feasibility and safety results.
Rico-Sánchez L, Garzón I, González-Andrades M, Ruíz-García A, Punzano M, Lizana-Moreno A, Muñoz-Ávila JI, Sánchez-Quevedo MDC, Martínez-Atienza J, Lopez-Navas L, Sanchez-Pernaute R, Oruezabal RI, Medialdea S, Gonzalez-Gallardo MDC, Carmona G, Sanbonmatsu-Gámez S, Perez M, Jimenez P, Cuende N, Campos A, Alaminos M.   +20 more
europepmc   +2 more sources

Intracoronary injection of haematopoietic precursor cells regenerates the borders, but not the core, of old myocardial scars

ESC Heart Failure, Volume 7, Issue 5, Page 2962-2971, October 2020., 2020
Abstract Aims Cell therapy regenerative potential is hindered by cell access to the infarct zone. We studied function recovery at the scar zone and its impact in global left ventricular function after intracoronary injection of haematopoietic precursor cells.
Alvaro Merino, Antoni Gaya, Javier Calvo, Ramon Rotger, Joana Nuñez   +4 more
wiley   +1 more source

Tractography of the uncinate fasciculus and the posterior cingulate fasciculus in patients with mild cognitive impairment and Alzheimer disease

Neurología (English Edition), 2014
Introduction: Brain tractography is a non-invasive medical imaging technique which enables in vivo visualisation and various types of quantitative studies of white matter fibre tracts connecting different parts of the brain.
A. Larroza, D. Moratal, V. D’ocón Alcañiz, E. Arana   +3 more
doaj   +1 more source

La ingeniería biomédica en la UC3M [PDF]

, 2014
Los rankings profesionales en las proyecciones del Departamento de Trabajo del gobierno de EE.UU. para el periodo 2008-2018, publicaba en 2010 la lista de las 50 carreras que, en su opinión, ofrecían las mejores oportunidades: en el área de ciencia y ...
Jorcano, José L.
core   +6 more sources

Ingeniería tisular y miocardio bioartificial

Cirugía Cardiovascular, 2011
La regeneración cardíaca requiere una cascada compleja de acontecimientos con numerosos factores, la mayoría aún no clarificados, que limitan la terapia celular y su traslación a la práctica clínica.
Juan Carlos Chachques, Jesús Herreros, Jorge Carlos Trainini, Noemí Lago, Lorena Díez-Solórzano, Valentín Tascón, Jorge Genovese   +6 more
doaj   +1 more source

Hidrogeles de colágeno acoplados con hidroxiapatita para aplicaciones en ingeniería tisular

TIP Revista Especializada en Ciencias Químico-Biológicas, 2020
Los hidrogeles basados en colágeno son redes tridimensionales (3D) con la capacidad de absorber agua y una alta biocompatibilidad para utilizarlos en la reparación de tejidos dañados.
Rosalina Lara-Rico, Jesús Alejandro Claudio-Rizo, Elia Martha Múzquiz-Ramos, Claudia Magdalena Lopez-Badillo   +3 more
doaj   +1 more source