Results 71 to 80 of about 245,129 (268)
Cerebral palsy (CP) is described as a group of permanent, nonprogressive movement disorders that cause physical disability in development and further affecting body movement and muscle coordination.
Vishnu Prasad +4 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Foreign bodies ingestion is considered as a common pediatric problem, it is mostly encountred in infants between 6months and 2 years. Ingestion of magnets was documented in only few reports.
Amine Ksia +6 more
doaj +1 more source
Toxic Ingestion/Ethylene Glycol Ingestion
Abstract Introduction Ethylene glycol overdose is an infrequent but potentially life-threatening ingestion that requires critical thinking and immediate interventions to prevent patient demise. As this is a less frequently encountered ingestion, most residents and fellows were not familiar with its management.
Mary Wittler, Mary Claire O'Brien
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Ingestion of Asbestos Fibers [PDF]
Feeding of baboons with crocidolite showed small numbers of asbestos needles 0.5-1 mum in ashed tissue of the gut wall, which probably came from iron-containing macrophages. It is suggested that pleural plaques and hyaline nodules in the peritoneum represent a hypersensitivity reaction to ferritin protein coating on asbestos fibers.
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
In summary, horses spend 60% or more of their time eating when grazing or when feed is available free choice. Grasses are their preferred food, but they supplement the grass with herbs and woody plants. Sweetened mixtures of oats and corn are the most preferred concentrate.
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Spent lead shot availability and ingestion by ring‐necked pheasants in South Dakota
Lead is toxic to all vertebrate species and ingestion of lead ammunition has been reported in >130 avian species. Research has primarily focused on the effects and exposure of spent lead shot on waterfowl with little information about effects on upland ...
Travis J. Runia, Alex J. Solem
doaj +1 more source

