Results 91 to 100 of about 226,248 (312)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Ingestion-rate method for measurement of clearance rates of the ctenophore Mnemiopsis leidyi

Aquatic Invasions, 2010
Clearance rates of small (about 12 mm oral-aboral length) Mnemiopsis leidyi were measured by means of the ingestion-rate method in order to compare with rates estimated from an equation (derived from Decker et al. 2004) used in previous studies. About 3 times higher clearance rates measured in the present study indicate that the estimated predation ...
V. Madsen, Caroline, Riisgård, Hans Ulrik   +1 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pediatric Foreign Body Ingestion: Analysis of Patient Characteristics and Surgical Treatment

Children
Background/Objectives: Foreign body (FB) ingestion is a common occurrence in children. We aimed to investigate the characteristics of patients hospitalized in the pediatric surgery department for FB ingestion and those requiring surgical treatment ...
Hee Jin Yeon, Sung Min Lee, Kyong Ihn, Jung-Tak Oh, Seok Joo Han, In Geol Ho   +5 more
doaj   +1 more source

Complications and management of acute copper sulphate poisoning; a case discussion

Journal of Occupational Medicine and Toxicology, 2011
Copper sulphate ingestion (accidental or deliberate) is a rare form of poisoning usually limited to the Indian subcontinent. Though the rates are on the decline, it is essential that physicians are aware of its lethal complications and management ...
Gamakaranage Champika SSK, Rodrigo Chaturaka, Weerasinghe Sajitha, Gnanathasan Ariaranee, Puvanaraj Visvalingam, Fernando Harshani   +5 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Microplastic in Sediments and Ingestion Rates in Three Edible Bivalve Mollusc Species in a Southern Philippine Estuary. [PDF]

Water Air Soil Pollut, 2022
Bonifacio PSP, Metillo EB, Romano EF.
europepmc   +1 more source

In vivo selection of resistant E. coli after ingestion of milk with added drug residues. [PDF]

, 2014
Antimicrobial resistance represents a major global threat to modern medicine. In vitro studies have shown that very low concentrations of drugs, as frequently identified in the environment, and in foods and water for human and animal consumption, can ...
Bicalho, Rodrigo Carvalho, Pereira, Richard Van Vleck, Siler, Julie D, Warnick, Lorin D   +3 more
core   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source