Results 191 to 200 of about 16,940 (269)

Epidemiology of Colon Cancer Screening in a Safety-Net Setting. [PDF]

AJPM Focus
Mahapatra E, Kee R, Shim K, Rowell C, Trick WE, Goldberg D.   +5 more
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Microstructural Damage Evolution and Interfacial Failure Mechanism of NC-UHPC Composites Under Seawater Wet-Dry Cycling. [PDF]

Materials (Basel)
Wei Z, Zheng Y, Jin L, Zhu W, Yang Y, Xie X.   +5 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Pregnancy-specific glycoproteins as molecular links between mesenchymal stromal cells and M2 macrophages in tissue repair: implications for cancer progression. [PDF]

Front Cell Dev Biol
da Silva Meirelles L.
europepmc   +1 more source

Editorial Commentary: Toward Off-the-Shelf Ureteral Substitutes Using iBTA "Biotubes". [PDF]

J Stem Cells Regen Med
Horiguchi A.
europepmc   +1 more source

Freeze-thaw recycling for fiber-resin separation in retired wind blades. [PDF]

Commun Eng
Ahmed K, Jiang X, Ashraf G, Qiang X.
europepmc   +1 more source

Design Verification Testing for Prefilled Syringes: A Structured Best-Practice Framework. [PDF]

Pharmaceutics
Boltres B, Laskina O, Andrejko B.
europepmc   +1 more source

Primary tuberculous mycobacterial granulomas provide a niche for superinfecting Mycobacterium abscessus. [PDF]

Nat Commun
Wee D, Pandey M, Chen Y, Lorenzini PA, Chow EW, Wang Y, Singhal A, Oehlers SH.   +7 more
europepmc   +1 more source