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CRISPR/Cas9-Based Knockout of GNAQ Reveals Differences in Host Cell Signaling Necessary for Egress of Apicomplexan Parasites [PDF]
Toxoplasma gondii and members of the genus Plasmodium are obligate intracellular parasites that leave their infected host cell upon a tightly controlled process of egress. Intracellular replication of the parasites occurs within a parasitophorous vacuole,
Paul-Christian Burda +4 more
doaj +3 more sources
Mechanisms of bunyavirus morphogenesis and egress
Unlike many segmented negative-sense RNA viruses, most members of the Bunyavirales bud at Golgi membranes, as opposed to the plasma membrane. Central players in this assembly process are the envelope glycoproteins, Gn and Gc, which upon translation undergo proteolytic processing, glycosylation and trafficking to the Golgi, where they interact with ...
Jake Barker +2 more
openaire +3 more sources
Regulatory T cells (Tregs) restrict overexuberant lymphocyte activation. While close proximity between Tregs and their suppression targets is important for optimal inhibition, and literature indicates that draining lymph nodes (LNs) may serve as a prime ...
Shuang Geng +10 more
doaj +1 more source
Brucella Egresses from Host Cells Exploiting Multivesicular Bodies
Host cell egress is a critical step in the life cycle of intracellular pathogens, especially in microbes capable of establishing chronic infections. The Gram-negative bacterium Brucella belongs to such a group of pathogens. Even though much has been done
Juan Manuel Spera +3 more
doaj +1 more source
Lassa virus (LASV) and Mopeia virus (MOPV) are two closely related, rodent-born mammarenaviruses. LASV is the causative agent of Lassa fever, a deadly hemorrhagic fever endemic in West Africa, whereas MOPV is non-pathogenic in humans.
Nicolas Baillet +9 more
doaj +1 more source
Senior Drivers’ Body Movement Strategies for Getting in and out of Cars: A Study by Vehicle Typology
During normal ageing, physical changes take place in the biomechanical, musculoskeletal, and psychomotor systems, that reduce strength, flexibility, motor coordination, balance, and precision of movements.
Susana C. F. Fernandes
doaj +1 more source
Mode choice behavior for access and egress connection to transit services
In the aims to investigate the potential market of Transportation Network Companies (TNCs) to serve as first/last mile connection for transit services, this study investigated the influential factors that affect transit users’ choices of access and ...
Ghazaleh Azimi +3 more
semanticscholar +1 more source
CAPG Is Required for Ebola Virus Infection by Controlling Virus Egress from Infected Cells
The replication of Ebola virus (EBOV) is dependent upon actin functionality, especially at cell entry through macropinocytosis and at release of virus from cells.
Hiroyuki Mori +7 more
doaj +1 more source
Baculovirus Entry and Egress from Insect Cells.
Baculoviruses are large DNA viruses of insects that are highly pathogenic in many hosts. In the infection cycle, baculoviruses produce two types of virions. These virion phenotypes are physically and functionally distinct, and each serves a critical role
G. Blissard, D. Theilmann
semanticscholar +1 more source
IL-33 promotes the egress of group 2 innate lymphoid cells from the bone marrow
Group 2 innate lymphoid cells (ILC2s) are effector cells within the mucosa and key participants in type 2 immune responses in the context of allergic inflammation and infection.
M. Stier +9 more
semanticscholar +1 more source

