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Hepatitis C Virus Assembly Imaging [PDF]
Viruses, 2011 Hepatitis C Virus (HCV) assembly process is the least understood step in the virus life cycle. The functional data revealed by forward and reverse genetics indicated that both structural and non-structural proteins are involved in the assembly process ...
Costin-Ioan Popescu +2 more
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Coronavirus membrane protein with a fluorescent protein tag enables particle tracking for the study of virus assembly and egress in live cells [PDF]
Journal of VirologyCoronavirus particles assemble at endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes and exit from host cells via secretory organelles that are not well defined.
Bereket Stefanos +7 more
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Structural Assembly of Qβ Virion and Its Diverse Forms of Virus-like Particles
Viruses, 2022 The coat proteins (CPs) of single-stranded RNA bacteriophages (ssRNA phages) directly assemble around the genomic RNA (gRNA) to form a near-icosahedral capsid with a single maturation protein (Mat) that binds the gRNA and interacts with the retractile ...
Jeng-Yih Chang +3 more
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Role of Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly
Frontiers in Immunology, 2018 Hepatitis C virus (HCV) glycoproteins E1 and E2 form a heterodimer to constitute viral envelope proteins, which play an essential role in virus entry. E1 does not directly interact with host receptors, and its functions in viral entry are exerted mostly ...
Yimin Tong +6 more
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Friend or Foe: The Role of the Cytoskeleton in Influenza A Virus Assembly
Viruses, 2019 Influenza A Virus (IAV) is a respiratory virus that causes seasonal outbreaks annually and pandemics occasionally. The main targets of the virus are epithelial cells in the respiratory tract.
Sukhmani Bedi, Akira Ono
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Trafficking of hepatitis C virus core protein during virus particle assembly.
PLoS Pathogens, 2011 Hepatitis C virus (HCV) core protein is directed to the surface of lipid droplets (LD), a step that is essential for infectious virus production. However, the process by which core is recruited from LD into nascent virus particles is not well understood.
Natalie A Counihan +2 more
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Frontiers in Microbiology, 2021 Flavivirus envelope protein (E) plays an important role in cellular infection, especially in virulence and antigenicity. E domain III of Tembusu virus (TMUV) is highly conserved among flaviviruses and contains four loop regions. However, the functions of
Tao Hu +50 more
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Rotavirus Particle Disassembly and Assembly In Vivo and In Vitro
Viruses, 2023 Rotaviruses (RVs) are non-enveloped multilayered dsRNA viruses that are major etiologic agents of diarrheal disease in humans and in the young in a large number of animal species.
Dunia Asensio-Cob +2 more
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The curious case of genome packaging and assembly in RNA viruses infecting plants
Frontiers in Genetics, 2023 Genome packaging is the crucial step for maturation of plant viruses containing an RNA genome. Viruses exhibit a remarkable degree of packaging specificity, despite the probability of co-packaging cellular RNAs.
Tushar Ranjan +9 more
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Mechanisms of Virus Assembly [PDF]
Annual Review of Physical Chemistry, 2015 Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review summarizes the physics that govern the processes by which capsids assemble within their host cells and in vitro.
Perlmutter, Jason D, Hagan, Michael F
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