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Hepatitis E Virus Assembly and Release [PDF]
Viruses, 2019 Hepatitis E is an underestimated threat to public health, caused by the hepatitis E virus (HEV). HEV is the most common cause of acute viral hepatitis in the world, with no available direct-acting antiviral treatment. According to a recent WHO report, 20
Xiaohui Ju, Qiang Ding
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Meclizine Inhibits Pseudorabies Virus Replication by Interfering With Virus Entry and Release [PDF]
Frontiers in Microbiology, 2021 Pseudorabies virus (PRV) is a pathogen that causes substantial economic losses to the swine industry. With the emergence and widespread of PRV variants since 2011 in China, current commercial vaccines cannot provide complete protection against PRV ...
Panrao Liu +10 more
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Foamy Virus Budding and Release [PDF]
Viruses, 2013 Like all other viruses, a successful egress of functional particles from infected cells is a prerequisite for foamy virus (FV) spread within the host. The budding process of FVs involves steps, which are shared by other retroviruses, such as interaction ...
Dirk Lindemann +2 more
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Exploring virus release as a bottleneck for the spread of influenza A virus infection in vitro and the implications for antiviral therapy with neuraminidase inhibitors. [PDF]
PLoS ONE, 2017 Mathematical models (MMs) have been used to study the kinetics of influenza A virus infections under antiviral therapy, and to characterize the efficacy of antivirals such as neuraminidase inhibitors (NAIs). NAIs prevent viral neuraminidase from cleaving
Laura E Liao +3 more
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Hepatitis C Virus: Assembly and Release of Virus Particles [PDF]
Journal of Biological Chemistry, 2010 Hepatitis C virus is a blood-borne virus that typically establishes a chronic infection in the liver, which often results in cirrhosis and hepatocellular carcinoma. Progress in understanding the complete virus life cycle has been greatly enhanced by the recent availability of a tissue culture system that produces infectious virus progeny.
Daniel M Jones
exaly +3 more sources
Glycometabolism regulates hepatitis C virus release.
PLoS Pathogens, 2021 HCV cell-culture system uses hepatoma-derived cell lines for efficient virus propagation. Tumor cells cultured in glucose undergo active aerobic glycolysis, but switch to oxidative phosphorylation for energy production when cultured in galactose.
Tao Yu +10 more
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Tetherin inhibits prototypic foamy virus release [PDF]
Virology Journal, 2011 Background Tetherin (also known as BST-2, CD317, and HM1.24) is an interferon- induced protein that blocks the release of a variety of enveloped viruses, such as retroviruses, filoviruses and herpesviruses.
Liang Chen +7 more
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ESCRT Requirements for Murine Leukemia Virus Release [PDF]
Viruses, 2016 The Murine Leukemia Virus (MLV) is a gammaretrovirus that hijack host components of the endosomal sorting complex required for transport (ESCRT) for budding.
Christina Bartusch, Reinhild Prange
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Viruses, 2021 The contribution of virus components to liberation of herpes simplex virus type 2 (HSV-2) progeny virions from the surface of infected cells is poorly understood.
Edward Trybala +6 more
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Viruses, 2022 Previously, we reported that an HIV-1 variant containing Met-to-Ile change at codon 50 and Val-to-Ile mutation at codon 151 of integrase (IN), HIV(IN:M50I/V151I), was an impaired virus.
Tomozumi Imamichi +4 more
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