Results 21 to 30 of about 2,979,740 (254)

Live Cell Imaging Reveals HBV Capsid Translocation from the Nucleus To the Cytoplasm Enabled by Cell Division

mBio, 2023
Hepatitis B virus (HBV) capsid assembly is traditionally thought to occur predominantly in the cytoplasm, where the virus gains access to the virion egress pathway.
Sofia Romero, Nuruddin Unchwaniwala, Edward L. Evans, Kevin W. Eliceiri, Daniel D. Loeb, Nathan M. Sherer   +5 more
doaj   +1 more source

The interaction between herpes simplex virus 1 genome and promyelocytic leukemia nuclear bodies (PML-NBs) as a hallmark of the entry in latency

Microbial Cell, 2016
Herpes simplex virus 1 (HSV-1) is a human pathogen that establishes latency in the nucleus of infected neurons in the PNS and the CNS. At the transcriptional level latency is characterized by a quasi-complete silencing of the extrachromosomal viral ...
Patrick Lomonte
doaj   +1 more source

Three-Dimensional Investigations of Virus-Associated Structures in the Nuclei with White Spot Syndrome Virus (WSSV) Infection in Red Swamp Crayfish (Procambarus clarkii)

Animals, 2022
White spot syndrome virus (WSSV) has been reported to cause severe economic loss in the shrimp industry. With WSSV being a large virus still under investigation, the 3D structure of its assembly remains unclear.
Yovita Permata Budi, Li-Chi Lin, Chang-Hsien Chung, Li-Li Chen, Yi-Fan Jiang   +4 more
doaj   +1 more source

Dynamics of HIV-1 assembly and release. [PDF]

, 2009
Assembly and release of human immunodeficiency virus (HIV) occur at the plasma membrane of infected cells and are driven by the Gag polyprotein. Previous studies analyzed viral morphogenesis using biochemical methods and static images, while dynamic and ...
Kräusslich Hans-Georg, Barbara Müller, William J. Godinez, Bräuchle Christoph, Müller, Barbara, Rohr Karl, Karl Rohr, Godinez, William J., William J Godinez, Lampe Marko, Eils, Roland, Godinez William J., Roland Eils, Rohr, Karl, Lampe, Marko, Ivanchenko Sergey, Lamb, Don C., Don C. Lamb, Marko Lampe, Bräuchle, Christoph, Eils Roland, Lamb Don C., Hans-Georg Kräusslich, Christoph Bräuchle, Kräusslich, Hans-Georg, Sergey Ivanchenko, Ivanchenko, Sergey, Don C Lamb, Müller Barbara   +28 more
core   +2 more sources

Efficient support of virus-like particle assembly by the HIV-1 packaging signal

eLife, 2018
The principal structural component of a retrovirus particle is the Gag protein. Retroviral genomic RNAs contain a ‘packaging signal’ (‘Ψ') and are packaged in virus particles with very high selectivity.
Mauricio Comas-Garcia, Tomas Kroupa, Siddhartha AK Datta, Demetria P Harvin, Wei-Shau Hu, Alan Rein   +5 more
doaj   +1 more source

Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures

Viruses, 2023
The formation of many double-stranded DNA viruses, such as herpesviruses and bacteriophages, begins with the scaffolding-protein-mediated assembly of the procapsid. Subsequently, the procapsid undergoes extensive structural rearrangement and expansion to
Hao Xiao, Junquan Zhou, Fan Yang, Zheng Liu, Jingdong Song, Wenyuan Chen, Hongrong Liu, Lingpeng Cheng   +7 more
doaj   +1 more source

Role of nonstructural protein NS2A in flavivirus assembly [PDF]

, 2008
Flavivirus nonstructural (NS) proteins are involved in RNA replication and modulation of the host antiviral response; however, evidence is mounting that some NS proteins also have essential roles in virus assembly.
Pijlman, G.P., Leung, J.Y., Khromykh, A.A., Hyde, J., Kondratieva, N., Mackenzie, J.M.   +5 more
core   +1 more source

Sequential packaging of RNA genomic segments during the assembly of Bluetongue virus. [PDF]

, 2014
Bluetongue virus (BTV), a member of the Orbivirus genus within the Reoviridae family, has a genome of 10 double-stranded RNA segments, with three distinct size classes.
Roy, Polly, Sung, Po-Yu, Po-yu Sung, Polly Roy   +3 more
core   +1 more source

The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles [PDF]

, 2008
Copyright @ 2008 American Society for Microbiology.The production of virus-like particles (VLPs) constitutes a relevant and safe model to study molecular determinants of virion egress.
Kien, F., Nicholls, JM, Bruzzone, R, Chan, C. M., Tsao, SW, Kien, F, Siu, Y. L., Escriou, N, Altmeyer, R., Nal, B., Nicholls, J. M., Chan, CM, Siu, YL, Lo, J, Peiris, J. S. M., Tsao, S. W., Teoh, KT, Nal, B, Teoh, K. T., Peiris, JSM, Altmeyer, R, Lo, J., Escriou, N., Bruzzone, R.   +23 more
core   +1 more source

Alterations of membrane curvature during influenza virus budding [PDF]

, 2014
Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Martyna, Agnieszka, Rossman, Jeremy S.
core   +1 more source